[HTML][HTML] Curcumin-zinc framework encapsulated microneedle patch for promoting hair growth

Y Yang, P Wang, Y Gong, Z Yu, Y Gan, P Li, W Liu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Hair loss is a growing esthetic condition driven by complex mechanisms that has numerous
psycho-social implications. Conventional drug applications usually focus on a single …

A lipid–polymer hybrid nanoparticle (LPN)-loaded dissolving microneedle patch for promoting hair regrowth by transdermal miR-218 delivery

Y Zhao, Y Tian, W Ye, X Wang, Y Huai, Q Huang… - Biomaterials …, 2023 - pubs.rsc.org
Alopecia is the most common multifactorial hair loss disorder, affecting almost 50% of the
population and even having a serious psychological impact on the patients. miR-218 has …

Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth

SF Lahiji, SH Seo, S Kim, M Dangol, J Shim, CG Li… - Biomaterials, 2018 - Elsevier
The interest in alternative material systems and delivery methods for treatment of
androgenetic alopecia has been increasing in the recent decades. Topical application of …

[HTML][HTML] A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch

Z Zhang, W Li, D Chang, Z Wei, E Wang, J Yu, Y Xu… - Bioactive materials, 2023 - Elsevier
Abstract A nanocomposite microneedle (ZCQ/MN) patch containing copper/zinc dual-doped
mesoporous silica nanoparticles loaded with quercetin (ZCQ) was developed as a …

Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis

A Yuan, Y Gu, Q Bian, R Wang, Y Xu, X Ma… - Journal of Controlled …, 2022 - Elsevier
Androgenetic alopecia (AGA), the most prevalent type of hair loss in clinic, is induced partly
by insufficient perifollicular vascularization. Here we designed a dissolvable microneedles …

Drug delivery system based on minoxidil nanoparticles promotes hair growth in C57BL/6 mice

N Nagai, Y Iwai, A Sakamoto, H Otake… - International Journal …, 2019 - Taylor & Francis
Purpose We designed formulations based on minoxidil (MXD) nanoparticles (N-MXD) and
examined whether N-MXD can increase drug delivery into the follicles. In addition, we …

Dissolving microneedle patch integrated with microspheres for long-acting hair regrowth therapy

M Yin, Y Zeng, HQ Liu, W Zhang, C Wang… - … Applied Materials & …, 2023 - ACS Publications
Androgenetic alopecia (AGA) is the most common type of progressive hair loss in both men
and women that severely reduces life quality and affects patients' self-esteem. Due to the …

[HTML][HTML] Hydrogel forming microneedles loaded with VEGF and Ritlecitinib/polyhydroxyalkanoates nanoparticles for mini-invasive androgenetic alopecia treatment

YW Ding, Y Li, ZW Zhang, JW Dao, DX Wei - Bioactive Materials, 2024 - Elsevier
Androgenetic alopecia (AGA), the most prevalent clinical hair loss, lacks safe and effective
treatments due to downregulated angiogenic genes and insufficient vascularization in the …

[HTML][HTML] Duo-role Platelet-rich Plasma: Temperature-induced fibrin gel and growth factors' reservoir for microneedles to promote hair regrowth

Y Sun, L Yang, L Du, Y Zhou, K Xu, J Chen… - Journal of Advanced …, 2024 - Elsevier
Introduction Alopecia concerns more than half our adult population. Platelet-rich plasma
(PRP) has been applied in skin rejuvenation and hair loss treatment. However, the pain and …

A drug‐free, hair follicle cycling regulatable, separable, antibacterial microneedle patch for hair regeneration therapy

Y Shi, J Zhao, H Li, M Yu, W Zhang… - Advanced …, 2022 - Wiley Online Library
The development of painless hair loss therapy without side‐effect is challenging. The dermal
papilla is the signal center of hair follicles and plays a key role in the regulation of their …