Nanomaterials for modulating the aggregation of β-amyloid peptides
Y Huang, Y Chang, L Liu, J Wang - Molecules, 2021 - mdpi.com
The aberrant aggregation of amyloid-β (Aβ) peptides in the brain has been recognized as
the major hallmark of Alzheimer's disease (AD). Thus, the inhibition and dissociation of Aβ …
the major hallmark of Alzheimer's disease (AD). Thus, the inhibition and dissociation of Aβ …
Advanced nanomaterials for modulating Alzheimer's related amyloid aggregation
X Shao, C Yan, C Wang, C Wang, Y Cao, Y Zhou… - Nanoscale …, 2023 - pubs.rsc.org
Alzheimer's disease (AD) is a common neurodegenerative disease that brings about
enormous economic pressure to families and society. Inhibiting abnormal aggregation of Aβ …
enormous economic pressure to families and society. Inhibiting abnormal aggregation of Aβ …
Nanotechnological approaches for targeting amyloid-β aggregation with potential for neurodegenerative disease therapy and diagnosis
Neurodegenerative disorders can arise as a result of amyloid-β production and misfolding of
its protein. The complex anatomy of the brain and the unresolved mechanics of the central …
its protein. The complex anatomy of the brain and the unresolved mechanics of the central …
Current strategies for modulating Aβ aggregation with multifunctional agents
Conspectus Alzheimer's disease (AD), as the primary cause of dementia, has seriously
affected millions of people worldwide and brought a very heavy financial and social burden …
affected millions of people worldwide and brought a very heavy financial and social burden …
Toward a rational design to regulate β-amyloid fibrillation for Alzheimer's disease treatment
X Han, G He - ACS chemical neuroscience, 2018 - ACS Publications
The last decades have witnessed a growing global burden of Alzheimer's disease (AD).
Evidence indicates that the onset and progression of AD is associated with β-amyloid (Aβ) …
Evidence indicates that the onset and progression of AD is associated with β-amyloid (Aβ) …
Inhibiting protein aggregation by small molecule-based colloidal nanoparticles
Conspectus Protein aggregation is associated with different human diseases such as
Alzheimer's, Huntington's, Parkinson's, diabetes type II, and cataracts. Currently no effective …
Alzheimer's, Huntington's, Parkinson's, diabetes type II, and cataracts. Currently no effective …
Nanoparticle cluster depolymerizes and removes amyloid fibrils for Alzheimer's disease treatment
Q Feng, N Wang, X Zhang, Y Mei, R Fu, J Chen… - Nano Today, 2023 - Elsevier
Aberrant amyloid-β (Aβ) fibrillation is the key event in Alzheimer's disease (AD), the
depolymerization and removal of which are being pursued with enthusiasm. Herein, a …
depolymerization and removal of which are being pursued with enthusiasm. Herein, a …
Antiamyloidogenic chemical/biochemical-based designed nanoparticle as artificial chaperone for efficient inhibition of protein aggregation
Protein aggregation is linked to variety of neurodegenerative disorders and other diseases.
Current research involves understanding the mechanism of protein aggregation, inhibiting …
Current research involves understanding the mechanism of protein aggregation, inhibiting …
The membrane axis of Alzheimer's nanomedicine
Alzheimer's disease (AD) is a major neurological disorder impairing its carrier's cognitive
function, memory, and lifespan. While the development of AD nanomedicine is still nascent …
function, memory, and lifespan. While the development of AD nanomedicine is still nascent …
Nanocomposites inhibit the formation, mitigate the neurotoxicity, and facilitate the removal of β-amyloid aggregates in Alzheimer's disease mice
Alzheimer's disease (AD) is a progressive and irreversible brain disorder. Recent studies
revealed the pivotal role of β-amyloid (Aβ) in AD. However, there is no conclusive indication …
revealed the pivotal role of β-amyloid (Aβ) in AD. However, there is no conclusive indication …