Recent findings underscore that some natural compounds are responsible for specific
biochemical effects, ie, the activation of redox‐sensitive intracellular pathways and …

Oxidative stress can induce cytotoxicity in neurons, which plays an important role in the
etiology of neuronal damage and degeneration. This study sought to determine the cellular …

Abstract Resveratrol (trans-3, 5, 4'-trihydroxystilbene) has received considerable attention
recently for the potential neuroprotective effects in neurodegenerative disorders where …

It was previously confirmed that hydrogen sulfide (H2S) has a neuroprotective effect,
preventing homocysteine‑induced neurotoxicity. However, the exact molecular mechanisms …

Neuronal cell death caused by oxidative stress is common in a variety of neural diseases
and can be investigated in detail in cultured HT22 neuronal cells, where the amino acid …

Oxidative stress plays an important role in brain aging and in neurodegenerative diseases.
New therapeutic agents are necessary to cross the blood–brain barrier and target disease …

Increasing lines of evidence show that resveratrol, a polyphenol compound contained in
several dietary products, exhibits cytoprotective actions. Notably, resveratrol activates sirtuin …

Polyphenols are known to exhibit wide spectrum of benefit for brain health and to protect
from several neurodegenerative diseases. The present study was sought to determine the …

Resveratrol, a polyphenol derived eg from red grapes, has been shown to mediate several
positive biological actions such as protection of cells against oxidative stress. It can also …

Background: An imbalance of free radicals and antioxidant defense systems in physiological
processes can result in protein/DNA damage, inflammation, and cellular apoptosis leading …