Systematic pan-cancer analysis reveals XCR1 as a Prognostic and Immunological Biomarker

L Cui, J Chen, C Li, Y Yu, S Xu - 2023 - researchsquare.com
Background Chemokines and their receptors play an important role in immune monitoring
and immune defense during the tumor growth and metastasis. However, their prognostic …

[HTML][HTML] Comprehensive analysis reveals XCL2 as a cancer prognosis and immune infiltration-related biomarker

W Chen, F Zou, T Song, Y Xia, J Xing, T Rao… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: XC Motif Chemokine Ligand 2 (XCL2) is a 114 amino acid, structurally
conserved chemokine involved in activating cytotoxic T cells. However, the …

Elevated expression of CXCL3 in colon cancer promotes malignant behaviors of tumor cells in an ERK-dependent manner

Y Cheng, X Yang, L Liang, H Xin, X Dong, W Li, J Li… - BMC cancer, 2023 - Springer
Background CXC chemokine ligand 3 (CXCL3) is a member of CXC-type chemokine family
that is identified as a major regulator in immune and inflammation responses. Recently …

An integrated pan-cancer analysis of 33 human cancers reveals the potential clinical implications and immunotherapeutic value of CXC motif chemokine ligand 13

H Zhang, H Yin, J Chen, Y Yuan - Frontiers in Oncology, 2022 - frontiersin.org
Background CXC Motif Chemokine Ligand 13 (CXCL13) plays a crucial part in the
pathogenesis of numerous lymphoproliferative disorders, inflammatory responses, and …

Proteomics-based analysis of differentially expressed proteins in the CXCR1-knockdown gastric carcinoma MKN45 cell line and its parental cell

W Hu, J Wang, G Luo, B Luo, C Wu… - Acta Biochim …, 2013 - academic.oup.com
CXC chemokine receptor types 1 (CXCR1), a cell-surface G-protein-coupled receptor has
been found to be associated with tumorigenesis, development, and progression of some …

Analysis of the prognosis and therapeutic value of the CXC chemokine family in head and neck squamous cell carcinoma

Y Li, T Wu, S Gong, H Zhou, L Yu, M Liang, R Shi… - Frontiers in …, 2021 - frontiersin.org
The CXC chemokines belong to a family which includes 17 different CXC members.
Accumulating evidence suggests that CXC chemokines regulate tumor cell proliferation …

Characterization of the prognostic values of the CXCR1-7 in clear cell renal cell carcinoma (ccRCC) microenvironment

Z Wu, Y Zhang, X Chen, W Tan, L He… - Frontiers in molecular …, 2020 - frontiersin.org
Background: As cancer immunotherapy has become a hot research topic, the values of CXC
chemokine receptors (CXCRs) in tumor microenvironment have been increasingly realized …

Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma

J Guan, J Weng, Q Ren, C Zhang, L Hu… - Bioscience …, 2021 - portlandpress.com
CXCL3 plays extensive roles in tumorigenesis in various types of human cancers through its
roles in tumor cell differentiation, invasion, and migration. However, the mechanisms of …

Comprehensive analysis of CXCR family members in lung adenocarcinoma with prognostic values

LT Hu, WJ Deng, ZS Chu, L Sun, CB Zhang… - BMC Pulmonary …, 2022 - Springer
Background The expression profiles and molecular mechanisms of CXC chemokine
receptors (CXCRs) in Lung adenocarcinoma (LUAD) have been extensively explored …