Synthetic hydrogel materials can recapitulate the natural cell microenvironment; however, it
is equally necessary that the gels maintain cell viability and phenotype while permitting …

Cost-effective and scalable synthetic matrices that support long-term expansion of human
pluripotent stem cells (hPSCs) have many applications, ranging from drug screening …

Clinical applications of human pluripotent stem cells (PSCs) are limited by the lack of
chemically well-defined scaffolds for cell expansion, differentiation, and implantation. In this …

A scalable and cost‐effective synthetic polymer substrate that supports robust expansion
and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with …

Stem cell therapy has attracted a great deal of attention for treating intractable diseases such
as cancer, stroke, liver cirrhosis, and ischemia. Especially, mesenchymal stem cells (MSCs) …

Chemically defined hydrogels are increasingly utilized to define the effects of extracellular
matrix (ECM) components on cellular fate determination of human embryonic and induced …

Highly porous polymers produced by polymerization of the continuous phase of a high
internal phase emulsion have been developed as scaffolds for 3D culture of human …

The development of three-dimensional matrices capable of recapitulating the main features
of native extracellular matrix and contribute for the establishment of a favorable …

Pluripotent stem cells hold great promise for many pharmaceutical and therapeutic
applications. However, the lack of scalable methodologies to expand these cells to clinically …

Human pluripotent stem cells (hPSCs) have the ability to differentiate into cells derived from
three germ layers and are an attractive cell source for cell therapy in regenerative medicine …