Inflammatory pain is the most common type of pain that is treated clinically. The use of
currently available treatments (classic analgesics-NSAIDs, paracetamol and opioids) is …

Neuropathic pain is characterised by both positive (hyperalgesia and allodynia) and
negative (sensory deficits) symptoms and remains intractable to many commonly used …

Anticonvulsants are widely used for the treatment of neuropathic pain. Here we review the
evidence for a number of peripheral and central changes after nerve injury that may provide …

Antiepileptic drugs (AEDs) are extensively used worldwide to treat a wide range of disorders
other than epilepsy, such as neuropathic pain, migraine, and bipolar disorder. Due to this …

Neuropathic pain, a form of chronic pain caused by injury to or disease of the peripheral or
central nervous system, is a formidable therapeutic challenge to clinicians because it does …

Neuropathic pain, whether of peripheral or central origin, is characterized by a neuronal
hyperexcitability in damaged areas of the nervous system. In peripheral neuropathic pain …

Background: Both neuropathic pain and migraine are now being treated with a variety of
newer antiepileptic drugs (AEDs). The proven efficacy of gabap in postherpetic neuralgia …

BACKGROUND: Many clinical pain states that are difficult to treat share a common feature of
sensitization of nociceptive pathways. Drugs that could normalize hyperexcitable neural …

An ideal anticonvulsant drug would prevent or inhibit excessive pathological neuronal
discharge without interfering with physiological neuronal activity and without producing …

Antiepileptic drugs (AEDs) are used to treat various nonepileptic central nervous system
(CNS) disorders, both in neurology and psychiatry. Most AEDs have multiple mechanisms of …