Regulation of enzyme activity and biocatalytic cascades on compartmentalized cellular
components is key to the adaptation of cellular processes such as signal transduction and …

In the discipline of bottom-up synthetic biology, vesicles define the boundaries of artificial
cells and are increasingly being used as biochemical microreactors operating in …

Cell organelles are subcellular structures entrapping a set of enzymes to achieve a specific
functionality. The incorporation of artificial organelles into cells is a novel medical paradigm …

Biological membrane-enclosed organelles are fascinating examples of spatially confined
nanoreactors for biocatalytic transformations such as cascade reactions involving multiple …

The bottom-up assembly of multicompartment artificial cells that are able to direct
biochemical reactions along a specific spatial pathway remains a considerable engineering …

Cell-sized vesicles have tremendous potential both as miniaturised pL reaction vessels and
in bottom-up synthetic biology as chassis for artificial cells. In both these areas the …

Life is fueled by multi-enzymatic tandem processes that display unmatched catalytic
efficiencies owing to certain features of the biological reactors such as …

The development of superior functional enzyme mimics (nanozymes) is essential for
practical applications, including point-of-care diagnostics, biotechnological applications …

Every living cell is a compartmentalized out-of-equilibrium system exquisitely able to convert
chemical energy into function. In order to maintain homeostasis, the flux of metabolites is …

Compartmentalization of functional biological units, cells, and organelles serves as an
inspiration for the development of biomimetic materials with unprecedented properties and …