Suppression of colorectal carcinogenesis by naringin

B Ansari, M Aschner, Y Hussain, T Efferth, H Khan - Phytomedicine, 2022 - Elsevier
Background Colorectal cancer is the third most malignant cancer worldwide. Despite novel
treatment options, the incidence and mortality rates of colon cancer continue to increase in …

Naringin, a natural dietary compound, prevents intestinal tumorigenesis in Apc Min/+ mouse model

YS Zhang, Y Li, Y Wang, SY Sun, T Jiang, C Li… - Journal of cancer …, 2016 - Springer
Purpose Naringin is a natural dietary flavonoid compound. We aimed to evaluate the effects
of naringin on intestinal tumorigenesis in the adenomatous polyposis coli multiple intestinal …

Natural dietary compound naringin prevents azoxymethane/dextran sodium sulfate-induced chronic colorectal inflammation and carcinogenesis in mice

YS Zhang, F Wang, SX Cui, XJ Qu - Cancer biology & therapy, 2018 - Taylor & Francis
Naringin, a natural occurring flavonoid compound, enriches in citrus fruits. We aimed to
evaluate the inhibitory effect of naringin on colitis and chronic inflammation-driven …

The variable effect on proliferation of a colon cancer cell line by the citrus fruit flavonoid Naringenin

HR Frydoonfar, DR McGrath… - Colorectal Disease, 2003 - Wiley Online Library
Objective Naringenin, a naturally occurring flavonoid found in citrus fruits, is known to have
anticarcinogenic properties. We have examined the effect of Naringenin on cell proliferation …

Naringin inhibits colorectal cancer cell growth by repressing the PI3K/AKT/mTOR signaling pathway

H Cheng, X Jiang, Q Zhang, J Ma… - Experimental and …, 2020 - spandidos-publications.com
In recent years, the incidence of colorectal cancer (CRC) has increased and research into
new treatment methods for CRC has become a hot topic. Naringin has an inhibitory effect on …

Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer

MSI Abaza, KY Orabi, E Al-Quattan… - Cancer cell international, 2015 - Springer
Background Natural products with diverse bioactivities are becoming an important source of
novel agents with medicinal potential. Cancer is a devastating disease that causes the death …

Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

A Rauf, MA Shariati, M Imran, K Bashir… - … Science and Pollution …, 2022 - Springer
Though the incidence of several cancers in Western societies is regulated wisely, some
cancers such as breast, lung, and colorectal cancer are currently rising in many low-and …

Naringin exerts therapeutic effects on mice colitis: a study based on transcriptomics combined with functional experiments

J Dong, Y Chen, F Yang, W Zhang, K Wei… - Frontiers in …, 2021 - frontiersin.org
Naringin has been shown to exert protective effects in an animal model of ulcerative colitis,
but detailed mechanisms remain unclear. This study aimed to investigate function and …

Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells

JM Yun, F Afaq, N Khan… - … : Published in cooperation …, 2009 - Wiley Online Library
Because of unsatisfactory treatment options for colon cancer, there is a need to develop
novel preventive approaches for this malignancy. One such strategy is through …

Chemopreventive and therapeutic potential of “naringenin,” a flavanone present in citrus fruits

IA Mir, AB Tiku - Nutrition and cancer, 2015 - Taylor & Francis
Cancer is one of the major causes of deaths in developed countries and is emerging as a
major public health burden in developing countries too. Changes in cancer prevalence …