The dendritic tree and brain disorders

VA Kulkarni, BL Firestein - Molecular and Cellular Neuroscience, 2012 - Elsevier
Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite arbors, and dendritic …

Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments

T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …

Molecular mechanisms of dendrite stability

AJ Koleske - Nature Reviews Neuroscience, 2013 - nature.com
In the developing brain, dendrite branches and dendritic spines form and turn over
dynamically. By contrast, most dendrite arbors and dendritic spines in the adult brain are …

Molecular mechanisms of dendrite morphogenesis

J Arikkath - Frontiers in cellular neuroscience, 2012 - frontiersin.org
Dendrites are key integrators of synaptic information in neurons and play vital roles in
neuronal plasticity. Hence, it is necessary that dendrite arborization is precisely controlled …

Structural and functional plasticity of dendritic spines–root or result of behavior?

CD Gipson, MF Olive - Genes, Brain and Behavior, 2017 - Wiley Online Library
Dendritic spines are multifunctional integrative units of the nervous system and are highly
diverse and dynamic in nature. Both internal and external stimuli influence dendritic spine …

Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease

TA Blanpied, MD Ehlers - Biological psychiatry, 2004 - Elsevier
Psychiatric and neurologic disorders ranging from mental retardation to addiction are
accompanied by structural and functional alterations of synaptic connections in the brain …

Dendrite structure

JC Fiala, KM Harris - Dendrites, 1999 - books.google.com
Dendrites are extensions of the cell body of the neuron specialized for receiving and
processing synaptic inputs. Dendrites exhibit enormously diverse forms. In many cases the …

Development and regulation of dendritic spine synapses

B Calabrese, MS Wilson, S Halpain - Physiology, 2006 - journals.physiology.org
Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic
component of most excitatory synapses in the brain. They play critical roles in synaptic …

Cell-intrinsic drivers of dendrite morphogenesis

SV Puram, A Bonni - Development, 2013 - journals.biologists.com
The proper formation and morphogenesis of dendrites is fundamental to the establishment
of neural circuits in the brain. Following cell cycle exit and migration, neurons undergo …

Molecular regulation of dendritic spine dynamics and their potential impact on synaptic plasticity and neurological diseases

P Maiti, J Manna, G Ilavazhagan, J Rossignol… - Neuroscience & …, 2015 - Elsevier
The structure and dynamics of dendritic spines reflect the strength of synapses, which are
severely affected in different brain diseases. Therefore, understanding the ultra-structure …