[HTML][HTML] The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

R Berni Canani, M Di Costanzo, L Leone - Clinical epigenetics, 2012 - Springer
Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in
the colon. In the last decade, multiple beneficial effects of butyrate at intestinal and …

[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease

K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …

[HTML][HTML] Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

RB Canani, M Di Costanzo, L Leone… - World journal of …, 2011 - ncbi.nlm.nih.gov
The multiple beneficial effects on human health of the short-chain fatty acid butyrate,
synthesized from non-absorbed carbohydrate by colonic microbiota, are well documented …

[HTML][HTML] Butyrate: a double-edged sword for health?

H Liu, J Wang, T He, S Becker, G Zhang, D Li, X Ma - Advances in nutrition, 2018 - Elsevier
Butyrate, a four-carbon short-chain fatty acid, is produced through microbial fermentation of
dietary fibers in the lower intestinal tract. Endogenous butyrate production, delivery, and …

[HTML][HTML] Butyrate-induced transcriptional changes in human colonic mucosa

SALW Vanhoutvin, FJ Troost, HM Hamer, PJ Lindsey… - PloS one, 2009 - journals.plos.org
Background Fermentation of dietary fiber in the colon results in the production of short chain
fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of …

The role of butyrate on colonic function

HM Hamer, D Jonkers, K Venema… - Alimentary …, 2008 - Wiley Online Library
Background Butyrate, a short‐chain fatty acid, is a main end‐product of intestinal microbial
fermentation of mainly dietary fibre. Butyrate is an important energy source for intestinal …

The butyrate story: old wine in new bottles?

W Scheppach, F Weiler - Current Opinion in Clinical Nutrition & …, 2004 - journals.lww.com
In the era of molecular biology our understanding of subcellular processes that ultimately
lead to inflammatory bowel disease or colorectal cancer has widened considerably. The …

Butyric acid from the diet: actions at the level of gene expression

JG Smith, WH Yokoyama… - Critical Reviews in Food …, 1998 - Taylor & Francis
A number of components present in the diet, although nutritionally nonessen-tial, have been
discovered to have beneficial effects toward both general health and disease …

Butyrate modulating effects on pro-inflammatory pathways in human intestinal epithelial cells

A Elce, F Amato, F Zarrilli, A Calignano, R Troncone… - Beneficial …, 2017 - brill.com
Butyrate acts as energy source for intestinal epithelial cells and as key mediator of several
immune processes, modulating gene expression mainly through histone deacetylation …

From the gut to the peripheral tissues: the multiple effects of butyrate

P Guilloteau, L Martin, V Eeckhaut… - Nutrition research …, 2010 - cambridge.org
Butyrate is a natural substance present in biological liquids and tissues. The present paper
aims to give an update on the biological role of butyrate in mammals, when it is naturally …