Associations of the Single Bovine Embryo Growth Media Metabolome with Successful Pregnancy

E Tsopp, K Kilk, E Taalberg, P Pärn, A Viljaste-Seera… - Metabolites, 2024 - mdpi.com
This study investigated whether metabolomic fingerprints of bovine embryo growth media
improve the prediction of successful embryo implantation. In this prospective cohort study …

Metabolites secreted by bovine embryos in vitro predict pregnancies that the recipient plasma metabolome cannot, and vice versa

E Gomez, N Canela, P Herrero, A Cereto, I Gimeno… - Metabolites, 2021 - mdpi.com
This work describes the use of mass spectrometry-based metabolomics as a non-invasive
approach to accurately predict birth prior to embryo transfer (ET) starting from embryo culture …

O-126 Blastocyst spent culture medium metabolite levels and reproductive outcomes

G Funda, İ Pala, V Emirdar, BS Seçinti… - Human …, 2024 - academic.oup.com
Study question Is there any relationship between blastocyst spent culture medium
metabolite levels and reproductive outcomes? Summary answer Metabolomic analysis of …

Metabolomic assessment of embryo viability

A Uyar, E Seli - Seminars in reproductive medicine, 2014 - thieme-connect.com
Preimplantation embryo metabolism demonstrates distinctive characteristics associated with
the developmental potential of embryos. On this basis, metabolite content of culture media …

Metabolomic profiling for selection of the most viable embryos in clinical IVF

GA Thouas, DK Gardner - Current Women's Health Reviews, 2010 - ingentaconnect.com
Along with standard morphological indicators of preimplantation embryo development,
information gained from novel “Omics” platforms is providing more detailed functional …

Blood plasma metabolomics predicts pregnancy in Holstein cattle transferred with fresh and vitrified/warmed embryos produced in vitro

E Gómez, P Salvetti, J Gatien, S Carrocera… - Journal of proteome …, 2020 - ACS Publications
Metabolomics may identify biomarkers in blood that differentiate pregnant from open embryo
recipients. Fresh and vitrified/warmed, in vitro-produced embryos were transferred to …

The metabolic signature of in vitro produced bovine embryos helps predict pregnancy and birth after embryo transfer

I Gimeno, P García-Manrique, S Carrocera… - Metabolites, 2021 - mdpi.com
In vitro produced (IVP) embryos show large metabolic variability induced by breed, culture
conditions, embryonic stage and sex and gamete donors. We hypothesized that the birth …

O-270: Non-invasive metabolomic profiling of human embryo culture media correlates with pregnancy outcome. Initial results of the Metabolomics Study Group for …

E Seli, D Sakkas, B Behr, P Nagy, JS Kwok… - Fertility and …, 2006 - fertstert.org
Objective More than 100,000 assisted reproductive technology (ART) cycles are started
yearly in the US Partly due to our inability to select the best embryo (s) to be transferred, a …

Development of a Novel Non-invasive Metabolomics Assay to Predict Implantation Potential of Human Embryos

S Cabello-Pinedo, H Abdulla, S Mas, A Fraire… - Reproductive …, 2024 - Springer
Can a set of metabolites present in embryo culture media correlate with embryo
implantation? Case-control study in two phases: discovery phase (101 samples) and …

Spent culture medium analysis from individually cultured bovine embryos demonstrates metabolomic differences

KJ Perkel, P Madan - Zygote, 2017 - cambridge.org
Spent culture medium can provide valuable information regarding the physiological state of
a bovine preimplantation embryos through non-invasive analysis of the sum/depleted …