Background Epigenome-wide association studies (EWAS) have identified DNA methylation
loci involved in adiposity. However, EWAS on adiposity in sub-Saharan Africans are lacking …

Abstract Background Type 2 diabetes (T2D) results from a complex interplay between
genetics and the environment. Several epigenome-wide association studies (EWAS) have …

Background The prevalence of obesity and its related chronic diseases have been
increasing especially in Asian countries. Obesity-related genetic variants have been …

Background: Adiposity is a risk factor for type 2 diabetes and cardiovascular disease,
suggesting an important role for adipose tissue in the development of these conditions. The …

Most epigenome-wide association studies to date have been conducted in blood. However,
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …

Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …

Background Obesity is an established risk factor for several common chronic diseases such
as breast and colorectal cancer, metabolic and cardiovascular diseases; however, the …

Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker
of body fat distribution. Although obesity disproportionately affects minority populations, few …

Obesity is an important component of the pathophysiology of chronic diseases. Identifying
epigenetic modifications associated with elevated adiposity, including DNA methylation …

Genome-wide association studies (GWAS) have identified> 300 loci associated with
measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for …