Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+ CD8+ T, CD8+ T, and γδ …

QM Cao, D Tian, CL Heffron, S Subramaniam… - Virology, 2019 - Elsevier
Immuno-stimulatory class I-restricted cytotoxic T lymphocytes (CTL) epitopes of porcine
reproductive and respiratory syndrome virus (PRRSV) are important for vaccine …

Identification of potential SLA-I-restricted CTL epitopes within the M protein of porcine reproductive and respiratory syndrome virus

C Liang, Q Xia, J Zhou, H Liu, Y Chen, Y Liu… - Veterinary …, 2021 - Elsevier
CD8+ cytotoxic T lymphocytes (CTLs), are essential for clearance of porcine reproductive
and respiratory syndrome virus (PRRSV) infection and regulation of host immune …

Immune responses and protection by vaccine and various vaccine adjuvant candidates to virulent porcine reproductive and respiratory syndrome virus

W Charerntantanakul, R Platt, W Johnson… - Veterinary immunology …, 2006 - Elsevier
Various vaccine adjuvant candidates were assessed with the modified-live porcine
reproductive and respiratory syndrome virus (MLV PRRSV)(Ingelvac® PRRS MLV) vaccine …

Construction and efficacy evaluation of novel swine leukocyte antigen (SLA) class I and class II allele-specific poly-T cell epitope vaccines against porcine …

D Tian, S Subramaniam, CL Heffron… - Journal of General …, 2020 - microbiologyresearch.org
Porcine reproductive and respiratory syndrome virus (PRRSV) causes an economically
important global swine disease. Here we report the development of subunit PRRSV-2 …

Porcine Reproductive and Respiratory Syndrome (PRRS) Virus-Specific Interferon-γ+ T-Cell Responses After PRRS Virus Infection or Vaccination with an Inactivated …

F Piras, S Bollard, F Laval, F Joisel, G Reynaud… - Viral …, 2005 - liebertpub.com
Although field studies have found porcine reproductive and respiratory syndrome (PRRSV)
inactivated vaccines to be beneficial in reducing losses linked to PRRSV infection, immune …

Pigs that recover from porcine reproduction and respiratory syndrome virus infection develop cytotoxic CD4+CD8+ and CD4+CD8- T-cells that kill virus infected …

CJ Chung, SH Cha, AL Grimm, D Ajithdoss, J Rzepka… - PloS one, 2018 - journals.plos.org
Porcine reproductive and respiratory syndrome virus (PRRSV) infection is difficult to control
because the virus undergoes antigenic variation during infection and also modulates the …

Recognition of highly diverse type-1 and-2 porcine reproductive and respiratory syndrome viruses (PRRSVs) by T-lymphocytes induced in pigs after experimental …

CJ Chung, SH Cha, AL Grimm, G Chung, KA Gibson… - PLoS …, 2016 - journals.plos.org
Background/Aim Live attenuated vaccines confer partial protection in pigs before the
appearance of neutralizing antibodies, suggesting the contribution of cell-mediated …

Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells

Y Li, E Mateu - Frontiers in immunology, 2021 - frontiersin.org
The present study delineates the interaction of a typical PRRSV1. 1 isolate 3267 (moderate
virulence) with in vitro derived pig conventional dendritic cells, cDC1, cDC2, and a CD14+ …

Identification of MHC-I-presented porcine respiratory and reproductive syndrome virus (PRRSV) peptides reveals immunogenic epitopes within several non-structural …

M Mötz, MR Stas, SE Hammer, T Duckova, F Fontaine… - Viruses, 2022 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most relevant
porcine pathogens worldwide. Active control of the disease relies on modified live virus …

Glycoprotein 5-Derived Peptides Induce a Protective T-Cell Response in Swine against the Porcine Reproductive and Respiratory Syndrome Virus

F Calderon-Rico, A Bravo-Patiño, I Mendieta… - Viruses, 2023 - mdpi.com
We analyzed the T-cell responses induced by lineal epitopes of glycoprotein 5 (GP5) from
PRRSV to explore the role of this protein in the immunological protection mediated by T …