The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method

J Lossouarn, E Beurrier, A Bouteau… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Phage therapy has (re) emerged as a serious possibility for combating multidrug-resistant
bacterial infections, including those caused by vancomycin-resistant Enterococcus faecium …

Evaluation of bacteriophage cocktails alone and in combination with daptomycin against daptomycin-nonsusceptible Enterococcus faecium

T Morrisette, KL Lev, GS Canfield… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Enterococcus faecium is a significant multidrug-resistant pathogen. Bacteriophage cocktails
are being proposed to complement antibiotic therapy. After a screen of 8 E. faecium strains …

[HTML][HTML] Defeating Antibiotic- and Phage-Resistant Enterococcus faecalis Using a Phage Cocktail in Vitro and in a Clot Model

L Khalifa, D Gelman, M Shlezinger, AL Dessal… - Frontiers in …, 2018 - frontiersin.org
The deteriorating effectiveness of antibiotics is propelling researchers worldwide towards
alternative techniques such as phage therapy: curing infectious diseases using viruses of …

Isolation and characterization of a novel Enterococcus faecalis bacteriophage φEF24C as a therapeutic candidate

J Uchiyama, M Rashel, Y Maeda… - FEMS Microbiology …, 2008 - academic.oup.com
Vancomycin-resistant Enterococcus faecalis (VRE) has become a significant threat in
nosocomial settings. Bacteriophage (phage) therapy is frequently proposed as a potential …

Bacteriophage-antibiotic combinations for Enterococcus faecium with varying bacteriophage and daptomycin susceptibilities

T Morrisette, KL Lev, R Kebriaei… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Concerns regarding increased prevalence of daptomycin (DAP)-resistant strains necessitate
novel therapies for Enterococcus faecium infections. Obligately lytic bacteriophages are …

Lytic bacteriophages facilitate antibiotic sensitization of Enterococcus faecium

GS Canfield, A Chatterjee, J Espinosa… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Enterococcus faecium, a commensal of the human intestine, has emerged as a hospital-
adapted, multidrug-resistant (MDR) pathogen. Bacteriophages (phages), natural predators …

Phage Cocktails can Prevent the Evolution of Phage-Resistant Enterococcus

S Wandro, P Ghatbale, H Attai, C Hendrickson… - BioRxiv, 2021 - biorxiv.org
Antibiotic resistant Enterococcus infections are a major health crisis that requires the
development of alternative therapies. Phage therapy could be an alternative to antibiotics …

In-vitro resensitization of multidrug resistant clinical isolates of Enterococcus faecium and faecalis through phage-antibiotic synergy

P Ghatbale, GP Sah, S Dunham, E Khong, A Blanc… - bioRxiv, 2024 - biorxiv.org
Bacteriophages are an increasingly attractive option for the treatment of antibiotic resistant
infections, but their efficacy is difficult to discern due to confounding effects of antibiotics …

Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia

ME Stellfox, C Fernandes, RK Shields, G Haidar… - Mbio, 2024 - Am Soc Microbiol
Enterococcus faecium is a member of the human gastrointestinal (GI) microbiota but can
also cause invasive infections, especially in immunocompromised hosts. Enterococci …

Bacteriophage Therapy Rescues Mice Bacteremic from a Clinical Isolate of Vancomycin-Resistant Enterococcus faecium

B Biswas, S Adhya, P Washart, B Paul… - Infection and …, 2002 - Am Soc Microbiol
Colonization of the gastrointestinal tract with vancomycin-resistant Enterococcus faecium
(VRE) has become endemic in many hospitals and nursing homes in the United States …