[HTML][HTML] The circulating 70 kDa heat shock protein (HSPA1A) level is a potential biomarker for breast carcinoma and its progression

GB de Freitas, L Penteado, MM Miranda, JR Filassi… - Scientific reports, 2022 - nature.com
The early diagnosis of breast cancer can improve treatment and prognosis. We sought to
evaluate whether the serum concentration of the 70 kDa heat shock protein (HSPA1A) was …

[HTML][HTML] Expression and clinical significance of HSPA2 in pancreatic ductal adenocarcinoma

H Zhang, H Gao, C Liu, Y Kong, C Wang, H Zhang - Diagnostic pathology, 2015 - Springer
Background It has been shown that heat shock-related 70-kDa protein 2 (HSPA2), a
member of the HSP70 family of heat shock proteins, is important for cancer cell growth and …

HspA1B Is a Prognostic Biomarker and Correlated With Immune Infiltrates in different subtypes of Breast Cancers

J He, H Wang - BioRxiv, 2019 - biorxiv.org
ABSTRACT Background Heat shock A1B, also known as HSP70kDa protein 1B, encodes a
70kDa heat shock protein which is a member of the heat shock protein 70 family. HspA1B is …

HSPA5 could be a prognostic biomarker correlated with immune infiltration in breast cancer

C Zhang, Q Liu, Y Zhou, J Hua, R Su, J Ai - Disease Markers, 2022 - Wiley Online Library
Background. Breast cancer (BC) is a frequent disease in females. The heat shock 70 kDa
protein 5 (HSPA5) has recently been discovered to have an important function in tumor …

[HTML][HTML] Various anti-HSPA2 antibodies yield different results in studies on cancer-related functions of heat shock protein A2

D Scieglinska, DR Sojka, A Gogler-Pigłowska… - International Journal of …, 2020 - mdpi.com
Heat shock proteins (HSPs) constitute a major part of the molecular chaperone system and
play a fundamental role in cell proteostasis. The HSPA (HSP70) family groups twelve highly …

Overexpressed HSPA2 correlates with tumor angiogenesis and unfavorable prognosis in pancreatic carcinoma

LL Zhai, Q Xie, CH Zhou, DW Huang, ZG Tang, TF Ju - Pancreatology, 2017 - Elsevier
Heat shock-related 70-kDa protein 2 (HSPA2) is known to correlate with tumor development
and progression. This work aimed to determine the expression and prognostic roles of …

[HTML][HTML] A human pan-cancer system analysis of heat shock protein family A member 5

C Deng, S Gong, L Lin, J Tang, X Pang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Heat shock protein family A member 5 (HSPA5) plays a pivotal role in the endoplasmic
reticulum (ER) stress response and unfolded protein response (UPR), both of which are …

Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer

YW Chang, CF Tseng, MY Wang, WC Chang, CC Lee… - Oncogene, 2016 - nature.com
Abstract Heat-shock protein 5 (HSPA5) is a marker for poor prognosis in breast cancer
patients and has an important role in cancer progression, including promoting drug …

[HTML][HTML] Plasma HSP90AA1 predicts the risk of breast cancer onset and distant metastasis

H Liu, Z Zhang, Y Huang, W Wei, S Ning, J Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Aim We aimed to develop and validate a comprehensive nomogram containing pre-
treatment plasma HSP90AA1 to predict the risk of breast cancer onset and metastasis …

[HTML][HTML] Comprehensive pan-cancer analysis of heat shock protein 110, 90, 70, and 60 families

L Yan, S Shen, A Wang, H Ding, Y Liu… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Here we carried out a panoramic analysis of the expression and prognosis of
HSP110, HSP90, HSP70, and HSP60 families in 33 types of cancer, with the aim of …