Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip

C Pascual‐Garrido, F Guilak, MF Rai… - Journal of …, 2018 - Wiley Online Library
Developmental dysplasia of the hip (DDH) in humans is a common condition that is
associated with hip pain, functional limitations, and secondary osteoarthritis (OA). Surgical …

Comparing hip dysplasia in dogs and humans: a review

K Willemsen, MM Möring, NI Harlianto… - Frontiers in veterinary …, 2021 - frontiersin.org
Hip dysplasia (HD) is common in both humans and dogs. This interconnection is because
humans and dogs descended from a common ancestor and therefore have a similar …

Gene expression in hip soft tissues in incipient canine hip dysplasia and osteoarthritis

RJ Todhunter, SJ Garrison, J Jordan… - Journal of …, 2019 - Wiley Online Library
Canine hip dysplasia and developmental dysplasia of the human hip share demographic,
phenotypic, and clinical features including the predisposition to develop osteoarthritis in …

Diagnosis, prevention, and management of canine hip dysplasia: a review

ER Schachner, MJ Lopez - Veterinary Medicine: Research and …, 2015 - Taylor & Francis
Canine hip dysplasia (CHD) is a polygenic and multifactorial developmental disorder
characterized by coxofemoral (hip) joint laxity, degeneration, and osteoarthritis (OA). Current …

Differential genetic regulation of canine hip dysplasia and osteoarthritis

Z Zhou, X Sheng, Z Zhang, K Zhao, L Zhu, G Guo… - PloS one, 2010 - journals.plos.org
Background Canine hip dysplasia (HD) is a common polygenic trait characterized by hip
malformation that results in osteoarthritis (OA). The condition in dogs is very similar to …

Mechanical osteoarthritis of the hip in a one medicine concept: a narrative review

I Tomé, S Alves-Pimenta, R Sargo, J Pereira… - BMC Veterinary …, 2023 - Springer
Human and veterinary medicine have historically presented many medical areas of potential
synergy and convergence. Mechanical osteoarthritis (MOA) is characterized by a gradual …

Definition and clinical diagnosis of Canine Hip Dysplasia; early diagnosis and treatment options.

A Vezzoni - 2008 - cabidigitallibrary.org
Hip dysplasia is the most widespread disease causing osteo-arthritis in dogs of all breeds.
The severity of hip dysplasia varies with the grade of osteoarthritis that develops during life …

[PDF][PDF] Hip dysplasia

WH Riser, WH Rhodes… - Texbook of Small …, 1985 - instituteofcaninebiology.org
Canine hip dysplasia is a complex disease. It is a concentration of factors from a pool of
genetic weaknesses and environmental stresses that fall into a programmed pattern of …

Pathogenesis of congenital hip dysplasia (CDH). A proposal

HM Frost - Veterinary and Comparative Orthopaedics and …, 1989 - thieme-connect.com
This article proposes four things.(I) A concentration of hip loads towards the rim of the
acetabular articular cartilage causes most CDH cases.(II) That load concentration retards …

An across-breed validation study of 46 genetic markers in canine hip dysplasia

L Mikkola, K Kyöstilä, J Donner, AK Lappalainen… - BMC genomics, 2021 - Springer
Background Canine hip dysplasia (CHD) is a common disease, with a complex genetic
background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an …