Depression is a neuropsychiatry medical condition with high prevalence, in which the
hypothalamic-pituitary-adrenal axis dysfunction has been postulated as the main cause. The …

In the present study, the protective effects of luteolin were investigated against psychological
stress-induced cognitive impairment. To emulate the psychological stress, mice received …

Background Late‐onset depression (LOD) is defined as primary depression that first
manifests after the age of 65. Luteolin (LUT) is a natural flavonoid that has shown promising …

Exposure to severe stress can lead to the development of neuropsychiatric disorders,
including post-traumatic stress disorder (PTSD). The cause of PTSD is dysregulation of the …

Venlafaxine (VLF) is an approved antidepressant that is claimed to have superior clinical
efficacy to comparable drugs. Recently, many studies showed the relationship between …

We investigated the effects of lamotrigine, aripiprazole and escitalopram administration and
experimental depression on lipid peroxidation (LP) and antioxidant levels in cortex of the …

The physiopathology of anxiety or depression related to diabetes is still poorly understood.
The treatment with antidepressant drugs is a huge challenge due to theirs adherence low …

This study examined the effects of lithium on gene expression and activity of the antioxidant
enzymes copper zinc superoxide dismutase (SOD1), manganese superoxide dismutase …

Aims Oxidative stress, impaired antioxidant defense and neuroinflammation are often
associated with the onset and progression of neuropsychiatric diseases. Conversely …

Venlafaxine is an approved antidepressant that is an inhibitor of both serotonin and
norepinephrine transporters. Medical treatment with oral venlafaxine can be beneficial to …