Male infertility is a women's health issue—research and clinical evaluation of male infertility is needed

KA Turner, A Rambhatla, S Schon, A Agarwal… - Cells, 2020 - mdpi.com
Infertility is a devastating experience for both partners as they try to conceive. Historically,
when a couple could not conceive, the woman has carried the stigma of infertility; however …

Infertility in men: advances towards a comprehensive and integrative strategy for precision theranostics

M Assidi - Cells, 2022 - mdpi.com
Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

The forgotten men: rising rates of male infertility urgently require new approaches for its prevention, diagnosis and treatment

V Ravitsky, S Kimmins - Biology of reproduction, 2019 - academic.oup.com
Over the past 40 years, sperm counts worldwide have halved and sperm quality has
declined alarmingly with 1 in 20 men currently facing reduced fertility [1]. Potential causes of …

[HTML][HTML] Limits of current male fertility testing

S Oehninger, W Ombelet - Fertility and Sterility, 2019 - Elsevier
In the current approach to male fertility testing, basic semen analysis has limitations as a
predictor of fertility status, and the technology is fraught with variability. Nonetheless, it …

Not every sperm is sacred; a perspective on male infertility

RJ Aitken - MHR: Basic science of reproductive medicine, 2018 - academic.oup.com
This article is a personal perspective on male infertility, a condition that is not only extremely
prevalent but also a major reason for couples to resort to ART. The introduction of ICSI as a …

Male infertility problem: a contemporary review on present status and future perspective

D Dissanayake, WLR Keerthirathna… - Gender and the …, 2019 - journals.sagepub.com
Semen quality plays a pivotal role in maintaining healthy fertilizing ability of spermatozoa.
Male infertility is a rising global problem with an increasing declining in male semen quality …

[HTML][HTML] Recent advances in understanding and managing male infertility

J Fainberg, JA Kashanian - F1000Research, 2019 - ncbi.nlm.nih.gov
Infertility is a prevalent condition affecting an estimated 70 million people globally. The
World Health Organization estimates that 9% of couples worldwide struggle with fertility …

Counting sperm does not add up any more: time for a new equation?

L Lefievre, K Bedu-Addo, SJ Conner… - …, 2007 - rep.bioscientifica.com
Although sperm dysfunction is the single most common cause of infertility, we have poor
methods of diagnosis and surprisingly no effective treatment (excluding assisted …

Male infertility caused by spermiogenic defects: lessons from gene knockouts

W Yan - Molecular and cellular endocrinology, 2009 - Elsevier
Spermiogenesis refers to the process by which postmeiotic spermatids differentiate into
elongated spermatids and eventually spermatozoa. During spermiogenesis, round …

Contribution of semen to early embryo development: fertilization and beyond

M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …