The utilization of hydrogen by micro-organisms as a source of reducing power or of protons
as final electron acceptors is mediated by metalloenzymes called hydrogenases. The need …

This article sets out to review the chemistry relating to the synthesis of structural and
functional analogues of the three classes of hydrogenases. This chemistry has grown …

The activation of molecular hydrogen is of interest both from a chemical and biological
viewpoint. The covalent bond of H2 is strong (436 kJ mol− 1). Its cleavage is catalyzed by …

Many microorganisms, such as methanogenic, acetogenic, nitrogen-fixing, photosynthetic,
or sulfate-reducing bacteria, metabolize hydrogen.[1, 2a] Hydrogen activation is mediated by …

Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the …

Many microorganisms can use molecular hydrogen as a source of electrons or generate it
by reducing protons. These reactions are catalysed by metalloenzymes of two types: NiFe …

Enzymes possessing the capacity to oxidize molecular hydrogen have developed
convergently three class of enzymes leading to:[FeFe]-,[NiFe]-, and [FeS]-cluster-free …

This report compares biomimetic hydrogen evolution reaction catalysts with and without the
amine cofactor (adtNH): Fe2 (adtNH)(CO) 2 (dppv) 2 (1 NH) and Fe2 (pdt)(CO) 2 (dppv) 2 …

Biological formation and consumption of molecular hydrogen (H2) are catalyzed by
hydrogenases, of which three phylogenetically unrelated types are known:[NiFe] …

Background:[NiFeSe] hydrogenases are metalloenzymes that catalyze the reaction H 2↔
2H++ 2e-. They are generally heterodimeric, contain three iron–sulfur clusters in their small …