Cell survival requires multiple factors, including appropriate proportions of molecular oxygen
and various antioxidants. Although most oxidative insults can be overcome by the cell's …

Reactive oxygen species (ROS) are products of normal metabolism and xenobiotic
exposure, and depending on their concentration, ROS can be beneficial or harmful to cells …

The oxygen paradox tells us that oxygen is both necessary for aerobic life and toxic to all life
forms. Reactive oxygen species (ROS) touch every biological and medical discipline …

Reactive oxygen species are widely generated in biological systems. Consequently humans
have evolved antioxidant defence systems that limit their production. Intracellular production …

Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …

Both extra-and intracellular stimuli elicit a wide variety of responses, such as cell survival,
proliferation, differentiation, and apoptosis, through regulation of cell signaling. Recent …

A variety of stimuli can induce cells to undergo apoptotic death. One of the most
reproducible inducers is mild oxidative stress, be it via exposure to hydrogen peroxide …

Oxidative stress, originating from reactive oxygen species and free radicals provides a
constant challenge to eukaryotic cell survival. While implicated in a number of degenerative …

Reactive oxygen species (ROS), whether produced endogenously as a consequence of
normal cell functions or derived from external sources, pose a constant threat to cells living …

The redox environment of the cell is currently thought to be extremely important to control
cell growth, differentiation, and apoptosis as many redox-sensitive proteins characterize …