Events in primate evolution are often dated by assuming a constant rate of substitution per
unit time, but the validity of this assumption remains unclear. Among mammals, it is well …

Using data from primates, we show that molecular clocks in sites that have been part of a
CpG dinucleotide in recent past (CpG sites) and non-CpG sites are of markedly different …

Two longstanding issues on the molecular clock hypothesis are studied in this article. First,
is there a global molecular clock in mammals? Although many authors have observed …

Generation time is an important determinant of a neutral molecular clock. There are several
human-specific life history traits that led to a substantially longer generation time in humans …

A statistical analysis of extensive DNA sequence data from primates, rodents, and
artiodacytls clearly indicates that no global molecular clock exists in mammals. Rates of …

The complete mitochondrial DNA (mtDNA) molecule of the hamadryas baboon, Papio
hamadryas, was sequenced and included in a molecular analysis of 24 complete …

The molecular clock has proved to be extremely valuable in placing timescales on
evolutionary events that would otherwise be difficult to date. However, debate has arisen …

One of the foundational results in molecular evolution is that the rate at which neutral
substitutions accumulate on a lineage equals the rate at which mutations arise. Traits that …

Molecular clocks have been used to date the divergence of humans and chimpanzees for
nearly four decades. Nonetheless, this date and its confidence interval remain to be firmly …

Comparative genomics allow us to search the human genome for segments that were
extensively changed in the last~ 5 million years since divergence from our common ancestor …