Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Precision medicine approaches to overcome resistance to therapy in head and neck cancers

S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …

The molecular landscape of head and neck cancer

CR Leemans, PJF Snijders, RH Brakenhoff - Nature Reviews Cancer, 2018 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments

B Solomon, RJ Young, D Rischin - Seminars in cancer biology, 2018 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) comprises a heterogeneous group of
tumors that arise from the squamous epithelium of the oral cavity, oropharynx, larynx and …

Recent advances and future directions in clinical management of head and neck squamous cell carcinoma

J Muzaffar, S Bari, K Kirtane, CH Chung - Cancers, 2021 - mdpi.com
Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …

Major changes in head and neck staging for 2018

W Lydiatt, B O'Sullivan, S Patel - American Society of Clinical …, 2018 - ascopubs.org
Oncologists should be aware of three major modifications and additions to staging head and
neck cancer that became effective in 2018. Oral cavity cancers have the addition of depth of …

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown… - Clinical cancer …, 2015 - AACR
Purpose: Current classification of head and neck squamous cell carcinomas (HNSCC)
based on anatomic site and stage fails to capture biologic heterogeneity or adequately …

Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …