Based on the “free radical theory” of disease, researchers have been trying to elucidate the
role of oxidative stress from free radicals in cardiovascular disease. Considerable data …

Ever since the discovery of free radicals, many hypotheses on the deleterious actions of
reactive oxygen species (ROS) have been proposed. However, increasing evidence …

Cardiovascular disease is the most common cause of mortality in the Western world and
accounts for up to a third of all deaths worldwide. Cardiovascular disease is multifactorial …

Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

Acute and chronic excessive intracellular increase of reactive oxygen species (ROS) is
involved in the development and progression of cardiovascular diseases. ROS are by …

The development of vascular disease has its origins in an initial insult to the vessel wall by
biological or mechanical factors. The disruption of homeostatic mechanisms leads to …

There is evidence that reactive oxygen species (ROS) are related to the development of
cardiovascular disease (CVD). Results from many studies support the hypothesis that ROS …

Despite some recent declines, cardiovascular disease (CVD) remains the major cause of
death in the United States and worldwide. Most recent advances in the treatment of CVD …

Over the last two decades, it has become increasingly clear that reactive oxygen species
(ROS), including free radicals are involved in cardiovascular disease. In recent years, there …

Oxygen radicals, and other reactive oxygen species, may play an important role in the
pathophysiology of atherosclerosis, stroke, and other cardiovascular diseases. Mechanisms …