Enhancing Fractionated Cancer Therapy: A Triple-Anthracene Photosensitizer Unleashes Long-Persistent Photodynamic and Luminous Efficacy
Y Wang, H Shen, Z Li, S Liao, B Yin… - Journal of the …, 2024 - ACS Publications
Conventional photodynamic therapy (PDT) is often limited in treating solid tumors due to
hypoxic conditions that impede the generation of reactive oxygen species (ROS), which are …
hypoxic conditions that impede the generation of reactive oxygen species (ROS), which are …
Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy
KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
In vitro demonstration of the heavy-atom effect for photodynamic therapy
A Gorman, J Killoran, C O'Shea, T Kenna… - Journal of the …, 2004 - ACS Publications
Photodynamic therapy (PDT) is an emerging treatment modality for a range of disease
classes, both cancerous and noncancerous. This has brought about an active pursuit of new …
classes, both cancerous and noncancerous. This has brought about an active pursuit of new …
Innovative strategies for enhanced tumor photodynamic therapy
Photodynamic therapy (PDT) is an approved and promising treatment approach that utilizes
a photosensitizer (PS) to produce cytotoxic reactive oxygen species (ROS) through …
a photosensitizer (PS) to produce cytotoxic reactive oxygen species (ROS) through …
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …
Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
Supramolecular photosensitizers rejuvenate photodynamic therapy
X Li, S Lee, J Yoon - Chemical Society Reviews, 2018 - pubs.rsc.org
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT)
has become a clinically promising approach for the treatment of a wide range of cancers and …
has become a clinically promising approach for the treatment of a wide range of cancers and …
Tailoring photosensitive ROS for advanced photodynamic therapy
Photodynamic therapy (PDT) has been considered a noninvasive and cost-effective
modality for tumor treatment. However, the complexity of tumor microenvironments poses …
modality for tumor treatment. However, the complexity of tumor microenvironments poses …
Enhanced photodynamic therapy for overcoming tumor hypoxia: From microenvironment regulation to photosensitizer innovation
J Du, T Shi, S Long, P Chen, W Sun, J Fan… - Coordination Chemistry …, 2021 - Elsevier
Photodynamic therapy (PDT) has garnered an increasing interest by both researchers and
clinicians as a non-invasive therapy that allows a selective treatment towards tumors …
clinicians as a non-invasive therapy that allows a selective treatment towards tumors …
Innovative strategies for hypoxic‐tumor photodynamic therapy
Despite its clinical promise, photodynamic therapy (PDT) suffers from a key drawback
associated with its oxygen‐dependent nature, which limits its effective use against hypoxic …
associated with its oxygen‐dependent nature, which limits its effective use against hypoxic …