Staphylococcal enterotoxins modulate the effector CD4+ T cell response by reshaping the gene expression profile in adults with atopic dermatitis
Staphylococcus aureus colonizes the skin of atopic dermatitis (AD) individuals, but the
impact of its enterotoxins on the chronic activation of CD4+ T cells demands further analysis …
impact of its enterotoxins on the chronic activation of CD4+ T cells demands further analysis …
Effects of topical application of a recombinant staphylococcal enterotoxin A on DNCB and dust mite extract-induced atopic dermatitis-like lesions in a murine model
BS Kim, JK Choi, HJ Jung, KH Park, YH Jang… - European Journal of …, 2014 - Springer
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease with biphasic T
cell-mediated abnormalities. Staphylococcal superantigens contribute to the exacerbation of …
cell-mediated abnormalities. Staphylococcal superantigens contribute to the exacerbation of …
Alpha‐toxin is produced by skin colonizing Staphylococcus aureus and induces a T helper type 1 response in atopic dermatitis
K Breuer, M Wittmann, K Kempe, A Kapp… - Clinical & …, 2005 - Wiley Online Library
Background Staphylococcus aureus is a well known trigger factor of atopic dermatitis (AD).
Besides the superantigens, further exotoxins are produced by S. aureus and may have an …
Besides the superantigens, further exotoxins are produced by S. aureus and may have an …
Staphylococcal enterotoxin induced IL‐5 stimulation as a cofactor in the pathogenesis of atopic disease: the hygiene hypothesis in reverse?
T Heaton, D Mallon, T Venaille, P Holt - Allergy, 2003 - Wiley Online Library
Background: The incidence of Staphylococcus aureus (S. aureus) colonization on the skin of
patients with atopic eczema/dermatitis syndrome (AEDS) is approximately 90% and a variety …
patients with atopic eczema/dermatitis syndrome (AEDS) is approximately 90% and a variety …
Staphylococcal α-toxin induces a higher T cell proliferation and interleukin-31 in atopic dermatitis
M Niebuhr, D Mamerow, A Heratizadeh… - International archives of …, 2011 - karger.com
Background: Patients with atopic dermatitis (AD) are frequently colonized with α-toxin-
producing Staphylococcus aureus which is in turn positively correlated with the severity of …
producing Staphylococcus aureus which is in turn positively correlated with the severity of …
Staphylococcal enterotoxin B induces specific IgG4 and IgE antibody serum levels in atopic dermatitis
Background Atopic dermatitis (AD) is a chronic recurrent inflammatory disease, with
prevalence of about 10–20% in children and 1–3% in adults. S taphylococcus aureus is …
prevalence of about 10–20% in children and 1–3% in adults. S taphylococcus aureus is …
Human dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarization
M Mandron, MF Ariès, RD Brehm, HS Tranter… - Journal of allergy and …, 2006 - Elsevier
BACKGROUND: Immune surveillance against microbes at sites of interface with
environment involves immediate recognition of pathogen-associated molecular patterns by …
environment involves immediate recognition of pathogen-associated molecular patterns by …
Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation
E Laborel-Préneron, P Bianchi, F Boralevi, P Lehours… - PLoS …, 2015 - journals.plos.org
Interactions between the immune system and skin bacteria are of major importance in the
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …
Increased expression of Toll-Like Receptor (TLR) 2 and TLR6 on peripheral blood monocytes by induction of Staphylococcal enterotoxin B during exacerbation of …
Background Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease that
can be triggered by various precipitating factors, including colonization by Staphylococcus …
can be triggered by various precipitating factors, including colonization by Staphylococcus …
DS–Nh as an experimental model of atopic dermatitis induced by Staphylococcus aureus producing staphylococcal enterotoxin C
T Yoshioka, I Hikita, T Matsutani, R Yoshida… - …, 2003 - Wiley Online Library
DS–Nh mice raised under conventional conditions spontaneously develop dermatitis similar
to human atopic dermatitis (AD), which is associated with staphylococcal infection. In the …
to human atopic dermatitis (AD), which is associated with staphylococcal infection. In the …
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