Emerging agents and regimens for AML

H Liu - Journal of hematology & oncology, 2021 - Springer
Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options,
depending solely on cytarabine+ anthracycline (7+ 3) intensive chemotherapy and …

Management of acute myeloid leukemia: current treatment options and future perspectives

M Fleischmann, U Schnetzke, A Hochhaus, S Scholl - Cancers, 2021 - mdpi.com
Simple Summary AML is a genetically heterogeneous disease with a median age of
diagnosis between 60 and 70 years. Thus, many AML patients are not eligible for intensive …

Novel therapy in Acute myeloid leukemia (AML): moving toward targeted approaches

ES Winer, RM Stone - Therapeutic advances in hematology, 2019 - journals.sagepub.com
Acute myeloid leukemia (AML) is a heterogenous and complex disease characterized by
rapid cellular proliferation, an aggressive clinical course, and generally high mortality. While …

How I treat relapsed or refractory AML

S DeWolf, MS Tallman - Blood, The Journal of the American …, 2020 - ashpublications.org
Abstract Treatment of relapsed or refractory acute myeloid leukemia (AML) has presented
challenges for hematologists for decades. Despite numerous clinical studies, outcomes are …

Novel therapies for AML: a round-up for clinicians

M Swaminathan, ES Wang - Expert Review of Clinical …, 2020 - Taylor & Francis
Introduction: Acute myeloid leukemia (AML) is a deadly disease associated with poor
outcomes. For over four decades, therapeutic options for AML were limited to high dose …

Precision therapy for acute myeloid leukemia

X Yang, J Wang - Journal of hematology & oncology, 2018 - Springer
Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous disease.
Despite advances in understanding the pathogenesis of AML, the standard therapy …

Recent drug approvals for acute myeloid leukemia

C Lai, K Doucette, K Norsworthy - Journal of hematology & oncology, 2019 - Springer
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with an
incidence that increases with age, and a generally poor prognosis. The disease is clinically …

[HTML][HTML] New drugs in acute myeloid leukemia

TM Kadia, F Ravandi, J Cortes, H Kantarjian - Annals of Oncology, 2016 - Elsevier
The standard therapy for acute myeloid leukemia (AML) has not changed meaningfully for
the past four decades. Improvements in supportive care and modifications to the dose and …

Recent advances in targeted therapies in acute myeloid leukemia

RS Bhansali, KW Pratz, C Lai - Journal of Hematology & Oncology, 2023 - Springer
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. While survival
for younger patients over the last several decades has improved nearly sixfold with the …

[HTML][HTML] Recent advances in the understanding and treatment of acute myeloid leukemia

J Watts, S Nimer - F1000Research, 2018 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease that
has a poor prognosis. Recent advances in genomics and molecular biology have led to a …