Advances in primary and stem cell derived neuronal cell culture techniques and abundance
of available neuronal cell types have enabled in vitro neuroscience as a substantial …

Most in vitro electrophysiology studies extract information and draw conclusions from
representative, temporally limited snapshot experiments. This approach bears the risk of …

Distributed microelectrode array (MEA) recordings from consistent, viable,≥ 500 μm thick
tissue preparations over time periods from days to weeks may aid in studying a wide range …

Three-dimensional in vitro models in microfluidic systems are promising tools for studying
cell biology, with complex models using multiple cell types combined with high resolution …

Quantitatively benchmarking similarities and differences between the in vivo central nervous
system and in vitro neuronal cultures can qualify discrepancies in functional responses and …

Cell culture in-vitro is a well-known method to develop cell and disease models for studying
physiologically relevant mechanisms and responses for various applications in life sciences …

Over the past century, robust methods were developed that enable the isolation, culture, and
dynamic observation of mammalian neuronal networks in vitro. But even if neuronal culture …

Microphysiological systems are an emerging field of biomimetic technologies which utilize
microfluidics to reconstitute tissue functions within an in vitro environment. Microfluidic organ …

Compartmentalized microfluidic neural cell culture platforms, which physically separate
axons from the neural soma using a series of microchannels, have been used for studying a …

The electrophysiological characterisation of cultured neurons is of paramount importance for
drug discovery, safety pharmacology and basic research in the neurosciences …