Transferrin (Tf) is a growth factor that transports iron in plasma. It is essential for proliferation
of activated T lymphocytes. Previous studies have suggested that peripheral blood cells are …

Transferrin is required by many cells for growth. Mitogen-induced T lymphocyte proliferation
is dependent on the presence of both interleukin 2 (IL-2; T-cell growth factor) and transferrin …

Transferrin receptors are expressed on proliferating cells and are required for their growth.
Transferrin receptors can be detected after, but not before, mitogenic stimulation of normal …

Transferrin (Tf) plays an important role during immunologic activation by donating iron to
activated lymphocytes. Therefore, synthesis by lymphomyeloid cells has been investigated …

Peripheral blood mononuclear cells (PBM) pulsed with lectin (PHA or Con A for 0.25-3 hr)
show a low expression of interleukin-2 and transferrin receptors (IL-2Rs, TfRs) and a mild …

We have produced a new rat IgG monoclonal antibody against the murine transferrin
receptor (TR). This antibody (C2F2) exhibits a surprisingly selective pattern of inhibition of …

Mitogen-activated normal human peripheral blood lymphocytes bind transferrin to specific
membrane receptors. In this study, lymphocytes stimulated with phytohaemagglutinin for 0 …

In order to distinguish between a requirement for iron and a possible additional requirement
for the iron-binding protein transferrin per se, the ability of mouse lymphocytes to proliferate …

Resting human T-lymphocytes show an elevated intracellular concentration of ferritin,
whereas transferrin receptors are not detectable. Stimulation by phytohemagglutinin …

Human transferrin was shown to greatly enhance the growth of lymphocytes in response to
PHA and antigens in vitro. The growth promoting action of transferrin could not be …