Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold

KC Rustad, VW Wong, M Sorkin, JP Glotzbach… - Biomaterials, 2012 - Elsevier
In this study, we examined the capacity of a biomimetic pullulan–collagen hydrogel to create
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells …

Adipose-derived stem cell-seeded hydrogels increase endogenous progenitor cell recruitment and neovascularization in wounds

R Kosaraju, RC Rennert, ZN Maan… - … Engineering Part A, 2016 - liebertpub.com
Adipose-derived mesenchymal stem cells (ASCs) are appealing for cell-based wound
therapies because of their accessibility and ease of harvest, but their utility is limited by poor …

In Vitro Evaluation of Scaffolds for the Delivery of Mesenchymal Stem Cells to Wounds

EA Wahl, FA Fierro, TR Peavy… - BioMed Research …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been shown to improve tissue regeneration in
several preclinical and clinical trials. These cells have been used in combination with three …

Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds

RK Garg, RC Rennert, D Duscher… - Stem cells …, 2014 - academic.oup.com
Effective skin regeneration therapies require a successful interface between progenitor cells
and biocompatible delivery systems. We previously demonstrated the efficiency of a …

Engineering fibrin hydrogels to promote the wound healing potential of mesenchymal stem cell spheroids

KC Murphy, J Whitehead, D Zhou, SS Ho, JK Leach - Acta biomaterialia, 2017 - Elsevier
Mesenchymal stem cells (MSCs) secrete endogenous factors such as vascular endothelial
growth factor (VEGF) and prostaglandin E2 (PGE 2) that promote angiogenesis, modulate …

Development of a UV crosslinked biodegradable hydrogel containing adipose derived stem cells to promote vascularization for skin wounds and tissue engineering

G Eke, N Mangir, N Hasirci, S MacNeil, V Hasirci - Biomaterials, 2017 - Elsevier
The aim of this study was to design a dermal substitute containing adipose derived stem
cells (ADSC) that can be used to improve the regeneration of skin on difficult wound beds by …

[HTML][HTML] Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells

NM Drzeniek, A Mazzocchi, S Schlickeiser… - …, 2021 - iopscience.iop.org
The therapeutic efficacy of clinically applied mesenchymal stromal cells (MSCs) is limited
due to their injection into harsh in vivo environments, resulting in the significant loss of their …

Autologous bone marrow–derived cultured mesenchymal stem cells delivered in a fibrin spray accelerate healing in murine and human cutaneous wounds

V Falanga, S Iwamoto, M Chartier, T Yufit… - Tissue …, 2007 - liebertpub.com
The nonhematopoietic component of bone marrow includes multipotent mesenchymal stem
cells (MSC) capable of differentiating into fat, bone, muscle, cartilage, and endothelium. In …

Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities

AY Clark, KE Martin, JR García, CT Johnson… - Nature …, 2020 - nature.com
Stem cell therapies are limited by poor cell survival and engraftment. A hurdle to the use of
materials for cell delivery is the lack of understanding of material properties that govern …

Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing

S Chen, J Shi, M Zhang, Y Chen, X Wang, L Zhang… - Scientific reports, 2015 - nature.com
The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) to
reach their full potential in the treatment of chronic wounds. A biocompatible multifunctional …