The baby lung was originally defined as the fraction of lung parenchyma that, in acute
respiratory distress syndrome (ARDS), still maintains normal inflation. Its size obviously …

Background: The “baby lung” concept originated as an offspring of computed tomography
examinations which showed in most patients with acute lung injury/acute respiratory distress …

Rationale: The open lung strategy aims at reopening (recruitment) of nonaerated lung areas
in patients with acute respiratory distress syndrome, avoiding tidal alveolar hyperinflation in …

The lungs of an extremely preterm infant≤ 28 weeks gestation are structurally and
biochemically immature and vulnerable to injury from positive pressure ventilation. A lung …

In the July 1999 issue of the Journal of the American Medical Association, Dr Leonard
Hudson proclaims that “the concept of ventilator-induced lung injury (VILI) has come of age.” …

Although only a small proportion of full term and late preterm infants require invasive
respiratory support, they are not immune from ventilator-associated lung injury. The process …

Despite a shift to noninvasive respiratory support, mechanical ventilation remains an
essential tool in the care of critically ill neonates. The availability of a variety of …

Lung volume, airway resistance, and compliance have been measured in 19 infants, 18 of
whom suffered from the respiratory distress syndrome (RDS) at birth, while the remaining …

Respiratory distress syndrome (RDS) is the most common respiratory diagnosis in preterm
infants. Surfactant therapy and mechanical ventilation using conventional or high-frequency …

Objective: Randomized controlled trials (RCTs) investigating various lung-protective
ventilation modes or strategies in newborn infants have failed to show clear differences in …