Cerebellar dysfunction relates to various psychiatric disorders, including autism spectrum
and depressive disorders. However, the physiological aspect is less advanced. Here, we …

The crosstalk between the nervous and immune systems has gained increasing attention for
its emerging role in neurological diseases. Radiation-induced brain injury (RIBI) remains the …

The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …

Peripheral inflammation is known to trigger a mirror inflammatory response in the brain,
involving brain's innate immune cells–microglia. However, the functional phenotypes, which …

Background Inflammation is a critical process for the progression of neuronal death in
neurodegenerative disorders. Microglia play a central role in neuroinflammation and may …

Persistent cognitive and behavioral symptoms that characterize many mental health
disorders arise from impaired neuroplasticity in several key corticolimbic brain regions …

Traumatic brain injury (TBI) is associated with an increased risk of cognitive, psychiatric, and
neurodegenerative complications that may develop after injury. Increased microglial …

Communication between neurons and microglia is essential for maintaining homeostasis in
the central nervous system (CNS) during both physiological and inflammatory conditions …

Psychological stress promotes the development and recurrence of anxiety and depressive
behavioral symptoms. Basic and clinical research indicates that stress exposure can …

Microglia are highly dynamic immune cells of the CNS and their dynamism is proposed to be
regulated by neuronal activities. However, the mechanisms underlying neuronal regulation …