Hereditary cancer syndromes are a heterogeneous group of genetic conditions that are
associated with an increased risk of developing cancer during lifespan. In affected women …

Simple Summary Genetic predisposition to a disease obliges women to face the fear of
transmitting cancer to their offspring. This might affect their willingness to seek pregnancy …

Purpose Because of increasing uptake of cancer genetic testing and the improving survival
of young patients with cancer, health care practitioners including oncologists will …

With the progress in cancer genetics and assisted reproductive technologies, it is now
possible for cancer gene mutation carriers not only to reduce cancer mortality through the …

Genetic cancer syndromes have identical clinical severity, limited therapeutic options,
reduced life expectancy, and risks of genetic transmission, as do other genetic or congenital …

Although all authors completed the disclosure declaration, the following author or immediate
family members indicated a financial interest. No conflict exists for drugs or devices used in …

Some rare families have a genetic mutation that is inherited either in the egg or the sperm
(germline mutation). It affects all cells of the body. People who inherit a germline mutation in …

Highlights•These ESMO Clinical Practice Guidelines provide recommendations for:○Fertility
preservation strategies in post-pubertal cancer patients, including those with hereditary …

Providers who care for women at risk for hereditary gynecologic cancers must consider the
impact of these conditions on reproductive and hormonal health. This document reviews …

Cancer Predisposition Syndromes (CPSs), also known as Hereditary Cancer Syndromes
(HCSs), represent a group of genetic disorders associated with an increased lifetime risk of …