A multifaceted role for polyamines in bacterial pathogens

P Shah, E Swiatlo - Molecular microbiology, 2008 - Wiley Online Library
Polyamines are polycationic molecules with a hydrocarbon backbone and multiple amino
groups. Descriptions of the physiological roles of polyamines have often been limited to their …

Polyamines: Emerging players in bacteria–host interactions

ML Di Martino, R Campilongo, M Casalino… - International journal of …, 2013 - Elsevier
Polyamines are small polycationic molecules found in almost all cells and associated with a
wide variety of physiological processes. In recent years it has become increasingly clear …

The roles of polyamines in microorganisms

AÖ Gevrekci - World Journal of Microbiology and Biotechnology, 2017 - Springer
Polyamines are small polycations that are well conserved in all the living organisms except
Archae, Methanobacteriales and Halobacteriales. The most common polyamines are …

Polyamine function in archaea and bacteria

AJ Michael - Journal of Biological Chemistry, 2018 - ASBMB
Most of the phylogenetic diversity of life is found in bacteria and archaea, and is reflected in
the diverse metabolism and functions of bacterial and archaeal polyamines. The polyamine …

[HTML][HTML] Polyamines reduce oxidative stress in Escherichia coli cells exposed to bactericidal antibiotics

AG Tkachenko, AV Akhova, MS Shumkov… - Research in …, 2012 - Elsevier
Bactericidal antibiotics (fluoroquinolones, aminoglycosides and cephalosporins) at their
sublethal concentrations were able to produce hydroxyl radicals, hydrogen peroxide and …

Polyamines in eukaryotes, bacteria, and archaea

AJ Michael - Journal of Biological Chemistry, 2016 - ASBMB
Polyamines are primordial polycations found in most cells and perform different functions in
different organisms. Although polyamines are mainly known for their essential roles in cell …

Polyamines and cancer: implications for chemotherapy and chemoprevention

SL Nowotarski, PM Woster… - Expert reviews in molecular …, 2013 - cambridge.org
Polyamines are small organic cations that are essential for normal cell growth and
development in eukaryotes. Under normal physiological conditions, intracellular polyamine …

Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

T Thomas*, TJ Thomas - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Polyamines are aliphatic cations with multiple functions and are essential for life. Cellular
polyamine levels are regulated by multiple pathways such as synthesis from amino acid …

A unifying model for the role of polyamines in bacterial cell growth, the polyamine modulon

M Yoshida, K Kashiwagi, A Shigemasa… - Journal of biological …, 2004 - ASBMB
We reported previously that the synthesis of specific proteins such as OppA, Cya, and RpoS
(σ 38), which are important for cell growth and viability, is stimulated by polyamines at the …

Polyamines as clinical laboratory tools

A Gugliucci - Clinica chimica acta, 2004 - Elsevier
Since their discovery by Antoni van Leeuwenhoek in 1678 until the recent development of
transgenic mice expressing proteins altering polyamine levels in a tissue-specific manner …