Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism

L Robertson, P Kesteven… - Cochrane Database of …, 2015 - cochranelibrary.com
Background Pulmonary embolism is a potentially life‐threatening condition in which a clot
can travel from the deep veins, most commonly in the leg, up to the lungs. Previously, a …

Direct oral anticoagulants in the treatment of pulmonary embolism

JB Eldredge, AC Spyropoulos - Current medical research and …, 2018 - Taylor & Francis
Objective: The objective of this review is to examine the management strategies for
pulmonary embolism (PE) with an emphasis of the role of direct oral anticoagulants …

Direct oral anticoagulants in the treatment of venous thromboembolism, with a focus on patients with pulmonary embolism: an evidence-based review

A Gómez-Outes, ML Suárez-Gea… - Vascular health and …, 2014 - Taylor & Francis
Pulmonary embolism (PE) is a relatively common cardiovascular emergency. PE and deep
vein thrombosis (DVT) are considered expressions of the same disease, termed as venous …

Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis

L Robertson, P Kesteven… - Cochrane Database of …, 2015 - cochranelibrary.com
Background Deep vein thrombosis (DVT) is a condition in which a clot forms in the deep
veins, most commonly of the leg. It occurs in approximately 1 in 1,000 people. If left …

Efficacy and safety of direct oral anticoagulants after pulmonary embolism: a meta-analysis

MC Vedovati, C Becattini… - International …, 2014 - internationaljournalofcardiology.com
Direct oral anticoagulants are as effective as conventional anticoagulant treatment after
pulmonary embolism with a reduction in major bleeding when the single-drug approach was …

Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of deep vein thrombosis

X Hui, M Li, J Li, J Tian, Q Wang, P Yan… - Cochrane Database …, 2023 - cochranelibrary.com
Background Deep vein thrombosis (DVT) is a condition in which a clot forms in the deep
veins, most commonly of the leg. It occurs in approximately one in 1000 people. If left …

New oral anticoagulants in the treatment of pulmonary embolism: efficacy, bleeding risk, and monitoring

KM Rudd, ELM Phillips - Thrombosis, 2013 - Wiley Online Library
Anticoagulation therapy is mandatory in patients with pulmonary embolism to prevent
significant morbidity and mortality. The mainstay of therapy has been vitamin‐K antagonist …

Non-vitamin K oral anticoagulants in patients with pulmonary embolism: a systematic review and meta-analysis of the literature

F Dentali, MND Di Minno, M Gianni… - Internal and emergency …, 2015 - Springer
Limited information exists on the safety and efficacy of non-vitamin K oral anticoagulants
(NOACs) in patients with pulmonary embolism (PE). The aim of this study is to evaluate the …

Anticoagulant treatment of pulmonary embolism: impact and implications of the EINSTEIN PE study

P Prandoni - European journal of haematology, 2012 - Wiley Online Library
Pulmonary embolism (PE), which can develop as a consequence of deep vein thrombosis
(DVT), is a serious and potentially fatal venous thromboembolic event. Patients with PE are …

Derivation of the non-inferiority margin for the evaluation of direct oral anticoagulants in the treatment of venous thromboembolism

MH Prins, AWA Lensing - Thrombosis journal, 2013 - Springer
Background Direct oral anticoagulants that target a single coagulation factor have been
developed as an alternative to standard therapies with heparin and/or vitamin K antagonists …