Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

In the past decade, experimental studies involving healthy human volunteers have revealed
that manipulations of the central serotonin (5-HT) system can produce quite specific …

Cognitive impairment is a key feature of schizophrenia and may be the most important
determinant of outcome in schizophrenia. This impairment is diffuse and may reflect …

Background: Symptoms of cognitive impairment such as poor concentration, memory loss
and difficulty with decision making are prevalent in patients with depression, but currently …

Executive function entails the interplay of a group of cognitive processes enabling the
individual to anticipate consequences, attain self-control, and undertake appropriate goal …

The indolamine, serotonin (5-hydroxytryptamine-5-HT) was identified and initially
characterized around the middle of the twentieth century and it is now known to participate in …

Growing evidence suggests that a compromised serotonergic system plays an important role
in the pathophysiology of Alzheimer's disease (AD). We assessed the expression of 5-HT …

Serotonergic dysfunction is thought to contribute to the pathophysiology of schizophrenia but
the evidence has not been systematically synthesised before. We therefore systematically …

Rationale Current treatments for schizophrenia adequately treat the positive symptoms of
schizophrenia but only modestly improve cognitive deficits. This review provides evidence …

Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …