Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease that is characterized by
progressive and irreversible scarring of the lung. The pathogenesis of IPF is not completely …
progressive and irreversible scarring of the lung. The pathogenesis of IPF is not completely …
Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fatal chronic lung disease characterized by
progressive scarring of the lung tissue, leading to respiratory failure. There is no cure for IPF …
progressive scarring of the lung tissue, leading to respiratory failure. There is no cure for IPF …
Lung fibroblasts, aging, and idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is an aging-associated, progressive, and irreversible lung
disease of unknown etiology, elusive pathogenesis, and very limited therapeutic options …
disease of unknown etiology, elusive pathogenesis, and very limited therapeutic options …
Fibroblast senescence in idiopathic pulmonary fibrosis
Y Lin, Z Xu - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …
The aging lung and idiopathic pulmonary fibrosis
S Gulati, VJ Thannickal - The American journal of the medical sciences, 2019 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is one of many clinical syndromes that are associated
with aging, and is increasing in both incidence and prevalence with the rapid rise in aging …
with aging, and is increasing in both incidence and prevalence with the rapid rise in aging …
Mechanistic links between aging and lung fibrosis
VJ Thannickal - Biogerontology, 2013 - Springer
Our understanding of the biology of aging has advanced significantly in recent years. This
has resulted in the recent formulation of the “hallmarks of aging” that include genomic …
has resulted in the recent formulation of the “hallmarks of aging” that include genomic …
Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic age-related lung disease with high mortality
that is characterized by abnormal scarring of the lung parenchyma. There has been a recent …
that is characterized by abnormal scarring of the lung parenchyma. There has been a recent …
Cellular senescence in idiopathic pulmonary fibrosis
DL Kellogg 3rd, DL Kellogg Jr, N Musi… - Current Molecular …, 2021 - Springer
Cellular senescence (CS) is increasingly implicated in the etiology of age-related diseases.
While CS can facilitate physiological processes such as tissue repair and wound healing …
While CS can facilitate physiological processes such as tissue repair and wound healing …
Idiopathic pulmonary fibrosis beyond the lung: understanding disease mechanisms to improve diagnosis and management
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disorder with an estimated
median survival time of 3–5 years after diagnosis. This condition occurs primarily in elderly …
median survival time of 3–5 years after diagnosis. This condition occurs primarily in elderly …
What have we learned from basic science studies on idiopathic pulmonary fibrosis?
T Yanagihara, S Sato, C Upagupta… - European Respiratory …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis is a fatal age-related lung disease characterised by
progressive and irreversible scarring of the lung. Although the details are not fully …
progressive and irreversible scarring of the lung. Although the details are not fully …