Mitochondria as molecular platforms integrating multiple innate immune signalings
M Monlun, C Hyernard, P Blanco, L Lartigue… - Journal of molecular …, 2017 - Elsevier
The immune system of vertebrates confers protective mechanisms to the host through the
sensing of stress-induced agents expressed during infection or cell stress. Among them, the …
sensing of stress-induced agents expressed during infection or cell stress. Among them, the …
Mitochondria: metabolic regulators of innate immune responses to pathogens and cell stress
L Lartigue, B Faustin - The international journal of biochemistry & cell …, 2013 - Elsevier
Higher vertebrates have developed protective mechanisms that can detect stress-induced
agents expressed during infection, stress or cellular damage. Innate sensing of these agents …
agents expressed during infection, stress or cellular damage. Innate sensing of these agents …
[HTML][HTML] Mitochondrial control of innate immune responses
S Chen, Z Liao, P Xu - Frontiers in immunology, 2023 - frontiersin.org
Mitochondria are versatile organelles and essential components of numerous biological
processes such as energy metabolism, signal transduction, and cell fate determination. In …
processes such as energy metabolism, signal transduction, and cell fate determination. In …
Macrophages and mitochondria: a critical interplay between metabolism, signaling, and the functional activity
Macrophages are phagocytic cells that participate in a broad range of cellular functions and
they are key regulators of innate immune responses and inflammation. Mitochondria are …
they are key regulators of innate immune responses and inflammation. Mitochondria are …
Mitochondria in innate immune signaling
B Banoth, SL Cassel - Translational Research, 2018 - Elsevier
Mitochondria are functionally versatile organelles. In addition to their conventional role of
meeting the cell's energy requirements, mitochondria also actively regulate innate immune …
meeting the cell's energy requirements, mitochondria also actively regulate innate immune …
[HTML][HTML] Mitochondria drive immune responses in critical disease
Mitochondria engage in multiple cellular and extracellular signaling pathways ranging from
metabolic control, antiviral and antibacterial host defense to the modulation of inflammatory …
metabolic control, antiviral and antibacterial host defense to the modulation of inflammatory …
Innate immunity and tolerance toward mitochondria
A Rongvaux - Mitochondrion, 2018 - Elsevier
Mitochondria are intracellular organelles that originate from a bacterial symbiont, and they
retain multiple features of this bacterial ancestry. The immune system evolved to detect the …
retain multiple features of this bacterial ancestry. The immune system evolved to detect the …
[HTML][HTML] Mitochondria: an organelle of bacterial origin controlling inflammation
A Meyer, G Laverny, L Bernardi, AL Charles… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a cellular and molecular response to infection and/or tissues injury. While a
suited inflammatory response in intensity and time allows for killing pathogens, clearing …
suited inflammatory response in intensity and time allows for killing pathogens, clearing …
Mitochondria in innate immune responses
The innate immune system has a key role in the mammalian immune response. Recent
research has demonstrated that mitochondria participate in a broad range of innate immune …
research has demonstrated that mitochondria participate in a broad range of innate immune …
Mitochondria: A master regulator in macrophage and T cell immunity
PS Liu, PC Ho - Mitochondrion, 2018 - Elsevier
Orchestrating biological activities of immune cells through metabolic reprogramming reveals
a new approach to harnessing immune responses. Increasing evidence reveals that the …
a new approach to harnessing immune responses. Increasing evidence reveals that the …