[HTML][HTML] Recent advances of organ-on-a-chip in cancer modeling research
X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J Xin, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …
remains one of the leading causes of death worldwide. Due to the unclear molecular …
[HTML][HTML] Tumor-on-a-chip: from bioinspired design to biomedical application
X Liu, J Fang, S Huang, X Wu, X Xie, J Wang… - Microsystems & …, 2021 - nature.com
Cancer is one of the leading causes of human death, despite enormous efforts to explore
cancer biology and develop anticancer therapies. The main challenges in cancer research …
cancer biology and develop anticancer therapies. The main challenges in cancer research …
Use and application of organ-on-a-chip platforms in cancer research
Y Yu, TT Zhou, L Cao - Journal of Cell Communication and Signaling, 2023 - Springer
Tumors are a major cause of death worldwide, and much effort has been made to develop
appropriate anti-tumor therapies. Existing in vitro and in vivo tumor models cannot reflect the …
appropriate anti-tumor therapies. Existing in vitro and in vivo tumor models cannot reflect the …
Organ-on-Chip platforms to study tumor evolution and chemosensitivity
Despite tremendous advancements in oncology research and therapeutics, cancer remains
a primary cause of death worldwide. One of the significant factors in this critical challenge is …
a primary cause of death worldwide. One of the significant factors in this critical challenge is …
[HTML][HTML] Organ on chip technology to model cancer growth and metastasis
Organ on chip (OOC) has emerged as a major technological breakthrough and distinct
model system revolutionizing biomedical research and drug discovery by recapitulating the …
model system revolutionizing biomedical research and drug discovery by recapitulating the …
On-chip recapitulation of the tumor microenvironment: A decade of progress
SM Giannitelli, V Peluzzi, S Raniolo, G Roscilli… - Biomaterials, 2024 - Elsevier
One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …
[HTML][HTML] Recent advances in cancer-on-a-chip tissue models to dissect the tumour microenvironment
Three-dimensional cancer-on-a-chip tissue models aim to replicate the key hallmarks of the
tumour microenvironment and allow for the study of dynamic interactions that occur during …
tumour microenvironment and allow for the study of dynamic interactions that occur during …
[HTML][HTML] Multi-organ-on-chip approach in cancer research
A Zuchowska, S Skorupska - Organs-on-a-Chip, 2022 - Elsevier
Cancer is the second cause of death worldwide after heart disease. Despite the still
developing anticancer therapies, the main challenge in cancer research is the establishing …
developing anticancer therapies, the main challenge in cancer research is the establishing …
Cancer Models on Chip: Paving the Way to Large‐Scale Trial Applications
Cancer kills millions of individuals every year all over the world (Global Cancer
Observatory). The physiological and biomechanical processes underlying the tumor are still …
Observatory). The physiological and biomechanical processes underlying the tumor are still …
[HTML][HTML] Cancer-on-chip: a 3D model for the study of the tumor microenvironment
E Cauli, MA Polidoro, S Marzorati, C Bernardi… - Journal of Biological …, 2023 - Springer
The approval of anticancer therapeutic strategies is still slowed down by the lack of models
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …