Abstract 'Dominant mutations in CAMK2B, encoding a subunit of the calcium/calmodulin-
dependent protein kinase II (CAMK2), a serine/threonine kinase playing a key role in …

Calcium/calmodulin-dependent protein kinase II (CAMK2) is one of the first proteins shown
to be essential for normal learning and synaptic plasticity in mice, but its requirement for …

Neurodevelopmental disorders are a complex and heterogeneous group of neurological
disorders characterized by their early-onset and estimated to affect more than 3% of children …

Calcium/calmodulin-dependent protein kinase II (CAMK2) plays fundamental roles in
synaptic plasticity that underlies learning and memory. Here, we describe a new recessive …

The abundantly expressed calcium/calmodulin‐dependent protein kinase II (CAMK2), alpha
(CAMK2A), and beta (CAMK2B) isoforms are essential for learning and memory formation …

With the recent findings that mutations in the gene encoding the α-subunit of
calcium/calmodulin-dependent protein kinase II (CAMK2A) causes a neurodevelopmental …

Background: The use of NGS technology has rapidly increased during the last decade, and
many new monogenic neurodevelopmental disorders have emerged. Pathogenic variants in …

Calcium/calmodulin-dependent protein kinases (CaMKs) are key mediators of calcium
signaling and underpin neuronal health. Although widely studied, the contribution of CaMKs …

The CAMK2B gene encodes the β‐subunit of calcium/calmodulin‐dependent protein kinase
II (CAMK2), an enzyme that has crucial roles in synaptic plasticity, especially in hippocampal …

CaMKIIα plays a fundamental role in learning and memory and is a key determinant of
synaptic plasticity. Its kinase activity is regulated by the binding of Ca2+/CaM and by …