Abstract Context Aggressive pituitary tumors (APTs) are characterized by unusually rapid
growth and lack of response to standard treatment. About 1% to 2% develop metastases …

Simple Summary ATRX is one of the most frequently mutated tumor suppressor genes in
human cancers. ATRX protein is a chromatin remodeler and transcriptional regulator that is …

Purpose Alterations in the promoter of the telomerase reverse transcriptase (TERT) gene are
a major mechanism of upregulating telomerase, which plays a crucial role in tumor …

Pituitary adenomas are rare in children and adolescents and although mostly benign, they
can sometimes be challenging to manage due to their locally invasive nature. In this study …

The prognostic value of BRAF V600E and TERT promoter mutation in papillary thyroid
carcinoma (PTC) is controversial. We examined alterations in BRAF V600E and TERT …

ATRX (alpha-thalassemia mental retardation X-linked) is one of the most frequently mutated
tumor suppressor genes in human cancers, especially in glioma, and recent findings …

Context: The aggressive role of TERT promoter mutations has been well established in
differentiated thyroid cancer but has not been established in anaplastic thyroid cancer …

The telomerase reverse transcriptase gene (TERT) encodes the reverse transcriptase
component of the telomerase complex, which is essential for telomere stabilization and cell …

Introduction: ATRX is a chromatin remodeling protein whose main function is the deposition
of the histone variant H3. 3. ATRX mutations are widely distributed in glioma, and correlate …

Background: Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies,
for which there is no effective treatment. Objective: In the present study, we aimed to …