Ecstasy induces apoptosis via 5-HT2A-receptor stimulation in cortical neurons
JP Capela, E Fernandes, F Remião, ML Bastos… - Neurotoxicology, 2007 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) is a psychoactive and
hallucinogenic drug of abuse. MDMA has been shown to produce neurotoxicity both in …
hallucinogenic drug of abuse. MDMA has been shown to produce neurotoxicity both in …
Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia
JP Capela, K Ruscher, M Lautenschlager, D Freyer… - Neuroscience, 2006 - Elsevier
Studies on 3, 4-methylenedioxymethamphetamine (“ecstasy”)-induced neurotoxicity mainly
focus on damage of serotonergic terminals. Less attention has been given to neuronal cell …
focus on damage of serotonergic terminals. Less attention has been given to neuronal cell …
Neurotoxicity of ecstasy metabolites in rat cortical neurons, and influence of hyperthermia
3, 4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) is a widely abused,
psychoactive recreational drug. There is growing evidence that the MDMA neurotoxic profile …
psychoactive recreational drug. There is growing evidence that the MDMA neurotoxic profile …
Neurotoxicity of ecstasy (MDMA): an overview
S Sarkar, L Schmued - Current pharmaceutical biotechnology, 2010 - ingentaconnect.com
“Ecstasy”(MDMA) is a powerful hallucinogenic drug which has raised concern worldwide
because of its high abuse liability. A plethora of studies have demonstrated that MDMA has …
because of its high abuse liability. A plethora of studies have demonstrated that MDMA has …
Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview
Abstract “Ecstasy”[(±)-3, 4-methylenedioxymethamphetamine, MDMA, XTC, X, E] is a
psychoactive recreational hallucinogenic substance and a major worldwide drug of abuse …
psychoactive recreational hallucinogenic substance and a major worldwide drug of abuse …
Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?
E Gouzoulis‐Mayfrank, J Daumann - Addiction, 2006 - Wiley Online Library
Background The popular dance drug ecstasy (3, 4‐methylenedioxymethamphetamine:
MDMA and some analogues) causes selective and persistent neurotoxic damage of central …
MDMA and some analogues) causes selective and persistent neurotoxic damage of central …
Neurotoxicity of MDMA: main effects and mechanisms
G Costa, K Gołembiowska - Experimental neurology, 2022 - Elsevier
Preclinical and clinical studies indicate that 3, 4-methylenedioxymethamphetamine
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …
The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons
3, 4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) and 2, 5-dimethoxy-4-
iodoamphetamine hydrochloride (DOI) are hallucinogenic amphetamines with addictive …
iodoamphetamine hydrochloride (DOI) are hallucinogenic amphetamines with addictive …
Studies of (±)-3, 4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profile
M Mueller, C Maldonado-Adrian, J Yuan… - … of Pharmacology and …, 2013 - ASPET
The neurotoxicity of (±)-3, 4-methylenedioxymethamphetamine (MDMA;“Ecstasy”) is
influenced by temperature and varies according to species. The mechanisms underlying …
influenced by temperature and varies according to species. The mechanisms underlying …
Neurotoxicity of “ecstasy” and its metabolites in human dopaminergic differentiated SH-SY5Y cells
“Ecstasy”(3, 4-methylenedioxymethamphetamine or MDMA) is a widely abused recreational
drug, reported to produce neurotoxic effects, both in laboratory animals and in humans …
drug, reported to produce neurotoxic effects, both in laboratory animals and in humans …