Time-restricted feeding mice a high-fat diet induces a unique lipidomic profile

AA Mehus, B Rust, JP Idso, B Hanson, H Zeng… - The Journal of …, 2021 - Elsevier
Time-restricted feeding (TRF) can reduce adiposity and lessen the co-morbidities of obesity.
Mice consuming obesogenic high-fat (HF) diets develop insulin resistance and hepatic …

Depot-dependent impact of time-restricted feeding on adipose tissue metabolism in high fat diet-induced obese male mice

T Bushman, TY Lin, X Chen - Nutrients, 2023 - mdpi.com
Time-restricted feeding (TRF) is known to be an effective strategy for weight loss and
metabolic health. TRF's effect on metabolism is complex and likely acts on various pathways …

Time-restricted feeding restores metabolic flexibility in adult mice with excess adiposity

L Yan, BM Rust, DG Palmer - Frontiers in Nutrition, 2024 - frontiersin.org
Introduction Obesity is prevalent with the adult population in the United States. Energy-
dense diets and erratic eating behavior contribute to obesity. Time-restricted eating is a …

Time-restricted feeding of a high-fat diet in male C57BL/6 mice reduces adiposity but does not protect against increased systemic inflammation

LB Delahaye, RJ Bloomer, MB Butawan… - Applied Physiology …, 2018 - cdnsciencepub.com
Time-restricted feeding (TRF) limits the duration of food availability without altering diet
composition and can combat obesity in humans and mice. For this study we evaluated the …

A high-fat diet enriched in medium chain triglycerides triggers hepatic thermogenesis and improves metabolic health in lean and obese mice

SA Rial, A Jutras-Carignan, KF Bergeron… - Biochimica et Biophysica …, 2020 - Elsevier
Obesity, liver steatosis and type 2 diabetes are major diseases partly imputed to energy-
dense diets rich in long chain triglycerides (LCT). The search for bioactive nutrients that help …

Time‐restricted feeding regulates lipid metabolism under metabolic challenges

Y Guo, C Livelo, GC Melkani - BioEssays, 2023 - Wiley Online Library
Dysregulation of lipid metabolism is a commonly observed feature associated with metabolic
syndrome and leads to the development of negative health outcomes such as obesity …

Nature of fatty acids in high fat diets differentially delineates obesity-linked metabolic syndrome components in male and female C57BL/6J mice

S El Akoum, V Lamontagne, I Cloutier… - Diabetology & metabolic …, 2011 - Springer
Background Adverse effects of high-fat diets (HFD) on metabolic homeostasis are linked to
adipose tissue dysfunction. The goal of this study was to examine the effect of the HFD …

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity

H Chung, W Chou, DD Sears, RE Patterson… - Metabolism, 2016 - Elsevier
Background Menopause is associated with significant hormonal changes that result in
increased total body fat and abdominal fat, amplifying the risk for metabolic syndrome and …

A short bout of HFD promotes long-lasting hepatic lipid accumulation

F Chiazza, TD Challa, FC Lucchini, D Konrad… - Adipocyte, 2016 - Taylor & Francis
abstract A short bout of high fat diet (HFD) impairs glucose tolerance and induces hepatic
steatosis in mice. Here, we aimed to elaborate on long-lasting effects of short-term high fat …

[PDF][PDF] Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

M Hatori, C Vollmers, A Zarrinpar, L DiTacchio… - Cell metabolism, 2012 - cell.com
While diet-induced obesity has been exclusively attributed to increased caloric intake from
fat, animals fed a high-fat diet (HFD) ad libitum (ad lib) eat frequently throughout day and …