Long-term efficacy of anti-PD1 therapy in Hodgkin lymphoma with and without allogenic stem cell transplantation

G Manson, JB Mear, C Herbaux, JM Schiano… - European Journal of …, 2019 - Elsevier
Introduction Long-term efficacy of anti-PD1 therapy and the need for a consolidation with
allogenic haematopoietic stem cell transplantation (allo-HSCT) remain unclear in patients …

[HTML][HTML] A phase II single arm study of nivolumab as maintenance therapy after autologous stem cell transplantation in patients with Hodgkin lymphoma at risk of …

C Bachier, H Schade, B Zoghi, A Ramakrishnan… - Blood, 2021 - Elsevier
Introduction: Autologous stem cell transplants (ASCT) are standard of care for patients with
primary refractory or recurrent Hodgkin lymphoma (HL). While transplant results in cure for …

Nivolumab for relapsed or refractory Hodgkin lymphoma: real-life experience

H Bekoz, M Ozbalak, N Karadurmus, S Paydas… - Annals of …, 2020 - Springer
Classical Hodgkin lymphoma (cHL) is considered a curable disease; however, in
approximately one-third of the responding patients, the disease relapses following …

Autologous stem cell transplantation after anti-PD-1 therapy for multiply relapsed or refractory Hodgkin lymphoma

RW Merryman, RA Redd, T Nishihori, J Chavez… - Blood …, 2021 - ashpublications.org
Autologous stem cell transplantation (ASCT) can be curative for patients with
relapsed/refractory Hodgkin lymphoma (HL). Based on studies suggesting that anti-PD-1 …

[HTML][HTML] Potential survival benefit for patients receiving allogeneic hematopoietic stem cell transplantation after nivolumab therapy for relapse/refractory Hodgkin …

C Martínez, C Carpio, I Heras, E Ríos-Herranz… - Biology of Blood and …, 2020 - Elsevier
Clinical trials have shown that nivolumab has remarkable activity against relapsed/refractory
classical Hodgkin lymphoma (cHL). However, the role of allogeneic hematopoietic stem cell …

Successful treatment with low-dose nivolumab in refractory Hodgkin lymphoma after allogeneic stem cell transplantation

M Onizuka, M Kojima, K Matsui, S Machida… - International journal of …, 2017 - Springer
Previous studies have reported that an antibody that blocks programmed cell death 1 (PD-1)
has therapeutic activity in patients with refractory/relapsed Hodgkin lymphoma (HL) …

Nivolumab for relapsed/refractory classic Hodgkin lymphoma after failure of autologous hematopoietic cell transplantation: extended follow-up of the multicohort single …

P Armand, A Engert, A Younes, M Fanale… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Genetic alterations causing overexpression of programmed death-1 ligands are
near universal in classic Hodgkin lymphoma (cHL). Nivolumab, a programmed death-1 …

Response-adapted anti-PD-1–based salvage therapy for Hodgkin lymphoma with nivolumab alone or in combination with ICE

MG Mei, HJ Lee, JM Palmer, R Chen… - Blood, The Journal …, 2022 - ashpublications.org
This phase 2 trial evaluated PET-adapted nivolumab alone or in combination with
ifosfamide, carboplatin, and etoposide (NICE) as first salvage therapy and bridge to …

Treatment of Hodgkin lymphoma relapsed after autologous stem cell transplantation

E Domingo-Domènech, A Sureda - Journal of Clinical Medicine, 2020 - mdpi.com
Although autologous stem cell transplantation (auto-HCT) is the standard of care for patients
with refractory/relapsed (R/R) classical Hodgkin's lymphoma (cHL), there is still a significant …

[HTML][HTML] Nivolumab is effective and reasonably safe in relapsed or refractory Hodgkin's lymphoma after allogeneic hematopoietic cell transplantation: a study from the …

C Herbaux, J Gauthier, P Brice, L Fornecker… - Blood, 2015 - Elsevier
BACKGROUND: It has been recently shown that nivolumab, a programmed death 1 (PD-1)
blocking antibody, had substantial therapeutic activity and an acceptable safety profile in …