Biodegradable polymeric nanoparticles increase risk of cardiovascular diseases by inducing endothelium dysfunction and inflammation
W Shi, ARM Fuad, Y Li, Y Wang, J Huang, R Du… - Journal of …, 2023 - Springer
Biodegradable polymers are expected to be an alternative to plastics. Because of its high
biocompatibility, poly (lactic-co-glycolic acid)(PLGA) is widely used in medicine. It has been …
biocompatibility, poly (lactic-co-glycolic acid)(PLGA) is widely used in medicine. It has been …
Phagocytosis of polymeric nanoparticles aided activation of macrophages to increase atherosclerotic plaques in ApoE−/− mice
T Yin, Y Li, Y Ren, ARM Fuad, F Hu, R Du… - Journal of …, 2021 - Springer
The unique physiochemical properties of nanomaterials have been widely used in drug
delivery systems and diagnostic contrast agents. The safety issues of biomaterials with …
delivery systems and diagnostic contrast agents. The safety issues of biomaterials with …
Anti-inflammatory nanoparticle for prevention of atherosclerotic vascular diseases
J Koga, T Matoba, K Egashira - Journal of atherosclerosis and …, 2016 - jstage.jst.go.jp
Recent technical innovation has enabled chemical modifications of small materials and
various kinds of nanoparticles have been created. In clinical settings, nanoparticle-mediated …
various kinds of nanoparticles have been created. In clinical settings, nanoparticle-mediated …
Long-term polystyrene nanoplastic exposure disrupt hepatic lipid metabolism and cause atherosclerosis in ApoE-/-mice
J Wen, H Sun, B Yang, E Song, Y Song - Journal of Hazardous Materials, 2024 - Elsevier
Nanoplastics (NPs) exposure is usually linked with abnormal inflammation and oxidative
stress, which are high-risk triggers of atherosclerosis; however, whether this exposure …
stress, which are high-risk triggers of atherosclerosis; however, whether this exposure …
PLA-PEG nanoparticles improve the anti-inflammatory effect of rosiglitazone on macrophages by enhancing drug uptake compared to free rosiglitazone
Among cardiovascular diseases, atherosclerosis remains the first cause of death in the
United States of America and Europe, as it leads to myocardial infarction or stroke. The high …
United States of America and Europe, as it leads to myocardial infarction or stroke. The high …
Targeted biodegradable nanoparticles for drug delivery to smooth muscle cells
S Kona, D Specht, M Rahimi, BP Shah… - … of Nanoscience and …, 2012 - ingentaconnect.com
Targeted delivery of therapeutic agents to prevent smooth muscle cell (SMC) proliferation is
important in averting restenosis (a narrowing of blood vessels). Since platelet derived …
important in averting restenosis (a narrowing of blood vessels). Since platelet derived …
An Emerging Role of Micro-and Nanoplastics in Vascular Diseases
SE Lee, HK Yoon, DY Kim, TS Jeong, YS Park - Life, 2024 - mdpi.com
Vascular diseases are the leading causes of death worldwide, and they are attributable to
multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary …
multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary …
Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery
CX Song, V Labhasetwar, H Murphy, X Qu… - Journal of controlled …, 1997 - Elsevier
Various drug-loaded poly (lactic-co-glycolic acid)(PLGA) nanoparticles (NP) were prepared
using an emulsification/solvent evaporation technique. Different emulsion systems were …
using an emulsification/solvent evaporation technique. Different emulsion systems were …
Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system
This research aims to develop targeted nanoparticles as drug carriers to the injured arterial
wall under fluid shear stress by mimicking the natural binding ability of platelets via …
wall under fluid shear stress by mimicking the natural binding ability of platelets via …
PLLA composites combined with delivery system of bioactive agents for anti-inflammation and re-endothelialization
The development of a biodegradable vascular scaffold (BVS) for the treatment of
cardiovascular diseases (CVDs) still requires some improvement. Among them, re …
cardiovascular diseases (CVDs) still requires some improvement. Among them, re …