What have we learned from basic science studies on idiopathic pulmonary fibrosis?
T Yanagihara, S Sato, C Upagupta… - European Respiratory …, 2019 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis is a fatal age-related lung disease characterised by
progressive and irreversible scarring of the lung. Although the details are not fully …
progressive and irreversible scarring of the lung. Although the details are not fully …
Understanding idiopathic pulmonary fibrosis-clinical features, molecular mechanism and therapies
Idiopathic pulmonary fibrosis (IPF) is a chronic lung fibrosing disease with high prevalence
that has a prognosis worse than many cancers. There has been a recent influx of new …
that has a prognosis worse than many cancers. There has been a recent influx of new …
The self-fulfilling prophecy of pulmonary fibrosis: a selective inspection of pathological signalling loops
AR Rackow, DJ Nagel, C McCarthy… - European …, 2020 - Eur Respiratory Soc
Pulmonary fibrosis is a devastating, progressive disease and carries a prognosis worse than
most cancers. Despite ongoing research, the mechanisms that underlie disease …
most cancers. Despite ongoing research, the mechanisms that underlie disease …
Revealing the pathogenic and ageing-related mechanisms of the enigmatic idiopathic pulmonary fibrosis (and chronic obstructive pulmonary disease)
P Spagnolo, U Semenzato - Current Opinion in Pulmonary …, 2022 - journals.lww.com
Several ageing mechanisms are dysregulated in the lungs of patients with IPF and COPD,
although how they contribute to disease development and progression remains elusive …
although how they contribute to disease development and progression remains elusive …
The epithelium in idiopathic pulmonary fibrosis: breaking the barrier
A Camelo, R Dunmore, MA Sleeman… - Frontiers in …, 2014 - frontiersin.org
Idiopathic pulmonary fibrosis is a progressive disease of unknown etiology characterized by
a dysregulated wound healing response that leads to fatal accumulation of fibroblasts and …
a dysregulated wound healing response that leads to fatal accumulation of fibroblasts and …
Lung fibroblasts, aging, and idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is an aging-associated, progressive, and irreversible lung
disease of unknown etiology, elusive pathogenesis, and very limited therapeutic options …
disease of unknown etiology, elusive pathogenesis, and very limited therapeutic options …
Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
JA Kropski, WE Lawson, LR Young… - Disease models & …, 2013 - journals.biologists.com
Idiopathic pulmonary fibrosis (IPF) is a progressive and often fatal lung disease for which
there is no known treatment. Although the traditional paradigm of IPF pathogenesis …
there is no known treatment. Although the traditional paradigm of IPF pathogenesis …
The role of aging in idiopathic pulmonary fibrosis
J Leung, Y Cho, RF Lockey, N Kolliputi - Lung, 2015 - Springer
Idiopathic pulmonary fibrosis (IPF) has been gathering interest in recent years and as such
this review will focus on the potential contributions that age plays on its onset and …
this review will focus on the potential contributions that age plays on its onset and …
Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model
A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …
Idiopathic pulmonary fibrosis
ZH Hoo, MKB Whyte - Thorax, 2012 - thorax.bmj.com
Idiopathic pulmonary fibrosis is a progressive lung disease that carries a poor prognosis and
for which there are no effective therapies. Although the excessive deposition of extracellular …
for which there are no effective therapies. Although the excessive deposition of extracellular …