Background Essentially all knowledge about adult hippocampal neurogenesis in humans
still comes from one seminal study by Eriksson et al. in 1998, although several others have …

In the rodent brain, diverse functions are topographically distributed within the hippocampus.
For instance, the dorsal (septal) hippocampus is involved in spatial memory, whereas the …

Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …

Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive
deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue …

The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

New neurons incorporate into the granular cell layer of the dentate gyrus throughout life.
Neurogenesis is modulated by behavior and plays a major role in hippocampal plasticity …

Adult-born hippocampal neurons are important for cognitive plasticity in rodents. There is
evidence for hippocampal neurogenesis in adult humans, although whether its extent is …

Adult hippocampal neurogenesis declines in aging rodents and primates. Aging humans are
thought to exhibit waning neurogenesis and exercise-induced angiogenesis, with a resulting …

Whether adult hippocampal neurogenesis (AHN) persists in adult and aged humans
continues to be extensively debated. A major question is whether the markers identified in …

The generation of new neurons in the adult mammalian brain is well-established for the
hippocampal dentate gyrus (DG). However, the role of neurogenesis in hippocampal …