New directions in allergic diseases: mechanism-based anti-inflammatory therapies

PJ Barnes - Journal of Allergy and Clinical Immunology, 2000 - Elsevier
Advances in our understanding of allergic inflammation have led to the development of
several novel anti-inflammatory drugs that target specific aspects of the inflammatory …

Recent advances in the development of anti-allergic drugs

H Nagai, H Teramachi, T Tuchiya - Allergology International, 2006 - jstage.jst.go.jp
Research over the past decade has provided information concerning the onset and
treatment of allergic diseases, including bronchial asthma, allergic rhinitis and atopic …

Novel biologicals for the treatment of allergic diseases and asthma

HTT Tan, K Sugita, CA Akdis - Current allergy and asthma reports, 2016 - Springer
Abstract Purpose of Review The development of biological therapies has rapidly progressed
during the last few years, and major advances were reported for the treatment of allergic …

Treatment strategies for allergy and asthma

ST Holgate, R Polosa - Nature Reviews Immunology, 2008 - nature.com
Allergic diseases have reached epidemic proportions worldwide. An understanding of the
cellular and soluble mediators that are involved in allergic inflammatory responses not only …

Future treatments of allergic diseases and asthma

RG Stirling, KF Chung - British medical bulletin, 2000 - academic.oup.com
Recent advances in the understanding of the inflammatory and immunological mechanisms
of allergic diseases have illuminated many potential therapeutic stratigies that may prevent …

The use of biologics for immune modulation in allergic disease

W van de Veen, M Akdis - The Journal of clinical …, 2019 - Am Soc Clin Investig
The rising prevalence of allergies represents an increasing socioeconomic burden. A
detailed understanding of the immunological mechanisms that underlie the development of …

Inflammation, inflammatory mediators, and mediator antagonists in asthma

SC Lazarus - The Journal of Clinical Pharmacology, 1998 - Wiley Online Library
Asthma is an inflammatory disease that involves mast cells, antigen‐presenting cells,
eosinophils, neutrophils, and TH2‐lymphocytes. These cells produce a broad array of …

Inflammation in asthma pathogenesis: role of T cells, macrophages, epithelial cells and type 2 inflammation

AH Alobaidi, AM Alsamarai… - Anti-Inflammatory & Anti …, 2021 - ingentaconnect.com
Asthma is a chronic disease with abnormal inflammatory and immunological responses. The
disease initiates by antigens in subjects with genetic susceptibility. However, environmental …

Cytokine-directed therapies for asthma

PJ Barnes - Journal of allergy and clinical immunology, 2001 - Elsevier
Increasing knowledge of the pathophysiologic roles of various cytokines in atopic diseases
has provided the basis for the development of novel therapies. Strategic approaches for …

Allergy and atopic diseases: an update on experimental evidence

D Verschoor, S von Gunten - International archives of allergy and …, 2019 - karger.com
Over the last decades, an increasing appearance of allergies and atopic disorders, such as
asthma, dermatitis, and rhinitis, has been observed. The mechanisms of these disorders …