Homing of hematopoietic stem cells (HSCs) into hematopoietic organs is a prerequisite for
the establishment of hematopoiesis during embryogenesis and after bone marrow …

Homing of hematopoietic stem cells (HSCs) into the bone marrow (BM) is a prerequisite for
establishment of hematopoiesis during development and following transplantation …

We investigated roles of α4 integrins during hematopoiesis using mutant and chimeric mice.
Yolk sac erythropoiesis and migration of hematopoietic progenitors to fetal liver, spleen, and …

ADHESIVE interactions mediated by integrins of the β1 subfamily1 are thought to be critical
in controlling differentiation and migration of blood cell precursors2–7. Here we report that …

The laminin receptor integrin α6 chain is ubiquitously expressed in human and mouse
hematopoietic stem and progenitor cells. We have studied its role for homing of stem and …

The cell surface receptor α4 integrin plays a critical role in the homing, engraftment, and
maintenance of hematopoietic progenitor cells (HPCs) in the bone marrow (BM). Down …

The mechanism of localization, migration, and regulation of hematopoiesis at different
stages of ontogeny is not well understood, but may relate to the specific adhesive …

The mechanisms of homing of endothelial progenitor cells (EPCs) to sites of ischemia are
unclear. Here, we demonstrate that ex vivo–expanded EPCs as well as murine …

OBJECTIVE: The aim of this study was to assess the potential of FLK1+ and vascular
endothelial (VE)-cadherin+ populations from different stages of embryonic development to …

Background Hematopoietic stem and progenitor cells can interact with their
microenvironment via integrins which are adhesion receptors consisting of α and β subunits …