[HTML][HTML] miR-6769b-5p targets CCND-1 to regulate proliferation in cadmium-treated placental trophoblasts: association with the impairment of fetal growth

YW Xiong, YJ Feng, T Wei, X Zhang, LL Tan… - Ecotoxicology and …, 2022 - Elsevier
Environmental cadmium (Cd) is positively associated with placental impairment and fetal
growth retardation. Nevertheless, its potential mechanisms remain unclear. microRNAs …

Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress

YW Xiong, XF Xu, HL Zhu, XL Cao, SJ Yi, XT Shi… - Journal of Hazardous …, 2021 - Elsevier
Abstract Cadmium (Cd), a well-known environmental pollutant, can lead to placental
insufficiency and fetal growth restriction. However, the underlying mechanism is unknown …

[HTML][HTML] The role of miRNAs in regulating the effect of prenatal cadmium exposure on ovarian granulosa cells in a transgenerational manner in female rats

J Liu, J Liao, C Zhang, L Zeng, C Zong, Y Lv, J Li… - Food and Chemical …, 2021 - Elsevier
Cadmium (Cd) is known to affect ovarian granulosa cells (GCs), but no information on the
transgenerational effects of Cd on GCs. In this study, pregnant Sprague-Dawley (SD) rats …

Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells

W Wang, G Liu, X Jiang, G Wu - Birth Defects Research, 2021 - Wiley Online Library
Abstract Background Cadmium (Cd) is a common heavy metal pollutant. Prenatal exposure
to Cd results in adverse effects on fetal development. Placental apoptosis, inflammation, and …

[HTML][HTML] Cadmium disturbs epigenetic modification and induces DNA damage in mouse preimplantation embryos

J Zhu, Z Huang, F Yang, M Zhu, J Cao, J Chen… - Ecotoxicology and …, 2021 - Elsevier
Cadmium is an environmental pollutant that has extensive deleterious effects on the
reproductive system. However, the mechanisms underlying the effects of cadmium on …

Maternal cadmium exposure during late pregnancy causes fetal growth restriction via inhibiting placental progesterone synthesis

YW Xiong, HL Zhu, Y Nan, XL Cao, XT Shi, SJ Yi… - Ecotoxicology and …, 2020 - Elsevier
Cadmium (Cd) is a major environmental pollutant. Maternal Cd exposure throughout
pregnancy caused fetal growth restriction (FGR). However, the pivotal time window of Cd …

[HTML][HTML] Gestational cadmium exposure impairs placental angiogenesis via activating GC/GR signaling

XT Shi, HL Zhu, XF Xu, YW Xiong, LM Dai… - Ecotoxicology and …, 2021 - Elsevier
Gestational exposure to environmental Cd caused placental angiogenesis impairment and
fetal growth restriction (FGR). However, its mechanism remained unclear. This study was to …

Increased expression of apoptotic markers in human full-term placenta after exposure to elevated environmental cadmium levels during pregnancy

L Phuapittayalert, N Tanasrivaroottanun… - … Science and Pollution …, 2021 - Springer
Cadmium (Cd), a toxic heavy metal, produces various forms of environmental
contaminations and health problems in human. In this study, we aimed to examine the …

[HTML][HTML] Maternal cadmium exposure impairs placental angiogenesis in preeclampsia through disturbing thyroid hormone receptor signaling

X Li, T Yu, M Zhai, Y Wu, B Zhao, C Duan… - Ecotoxicology and …, 2022 - Elsevier
Cadmium is a ubiquitous environmental pollutant, which can increase the risk of
preeclampsia. This study was designed to determine the mechanism of cadmium exposure …

Cadmium inhibits placental trophoblast cell migration via miRNA regulation of the transforming growth factor beta (TGF-β) pathway

SA Brooks, RC Fry - Food and chemical toxicology, 2017 - Elsevier
Preeclampsia (PE), a condition during pregnancy that involves high blood pressure and
proteinuria, is potentially fatal to both mother and child. PE currently has no known etiology …