Circulating tumor cells: technologies and their clinical potential in cancer metastasis
Circulating tumor cells (CTCs) are single cells or clusters of cells within the circulatory
system of a cancer patient. While most CTCs will perish, a small proportion will proceed to …
system of a cancer patient. While most CTCs will perish, a small proportion will proceed to …
Circulating tumour cells—a bona fide cause of metastatic cancer
NJ Caixeiro, N Kienzle, SH Lim, KJ Spring… - Cancer and Metastasis …, 2014 - Springer
Circulating tumour cells (CTCs) are emerging as important prognostic markers and have
potential clinical utility as tumour biomarkers for targeted cancer therapy. Although CTCs …
potential clinical utility as tumour biomarkers for targeted cancer therapy. Although CTCs …
Circulating tumor cells: from bench to bedside
Circulating tumor cells (CTCs) represent a surrogate biomarker of hematogenous
metastases. In recent years, their detection has gained increasing interest. There is ample …
metastases. In recent years, their detection has gained increasing interest. There is ample …
Circulating tumor cells: utopia or reality?
V Conteduca, R Zamarchi, E Rossi, V Condelli… - Future …, 2013 - Taylor & Francis
Circulating tumor cells (CTCs) could be considered a sign of tumor aggressiveness, but
highly sensitive and specific methods of CTC detection are necessary owing to the rarity and …
highly sensitive and specific methods of CTC detection are necessary owing to the rarity and …
Utilizing circulating tumor cells: challenges and pitfalls
G Attard, JS de Bono - Current opinion in genetics & development, 2011 - Elsevier
Circulating tumor cells (CTC) detected in the blood of cancer patients could be used for risk-
stratification, molecular subclassification and as an intermediate end-point in therapeutic …
stratification, molecular subclassification and as an intermediate end-point in therapeutic …
Circulating tumor cells: the substrate of personalized medicine?
BT Greene, AD Hughes, MR King - Frontiers in oncology, 2012 - frontiersin.org
Circulating tumor cells (CTCs) are believed to be responsible for the development of
metastatic disease. Over the last several years there has been a great interest in …
metastatic disease. Over the last several years there has been a great interest in …
The role of circulating tumor cells in the metastatic cascade: biology, technical challenges, and clinical relevance
Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Preclinical models to study patient-derived circulating tumor cells and metastasis
Circulating tumor cells (CTCs) that are detached from the tumor can be precursors of
metastasis. The majority of studies focus on enumeration of CTCs from patient blood to …
metastasis. The majority of studies focus on enumeration of CTCs from patient blood to …
Looking back, to the future of circulating tumor cells
TW Friedlander, G Premasekharan, PL Paris - Pharmacology & therapeutics, 2014 - Elsevier
Detection and analysis of circulating tumor cells (CTCs) from patients with metastatic
malignancies have become active areas of research in recent years. CTC enumeration has …
malignancies have become active areas of research in recent years. CTC enumeration has …
Circulating tumor cells
In most solid tumors, it is distant metastases rather than the primary tumor which limit the
prognosis. Distant metastases are caused by circulating tumor cells (CTCs) which actively …
prognosis. Distant metastases are caused by circulating tumor cells (CTCs) which actively …